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12/27/2018 8:56:32 AM | Browse: 312 | Download: 264
Publication Name World Journal of Gastroenterology
Manuscript ID 43054
Country/Territory China
2018-11-09 02:06
Peer-Review Started
2018-11-12 02:29
To Make the First Decision
2018-11-29 09:23
Return for Revision
2018-12-07 01:32
2018-12-08 02:31
Second Decision
2018-12-13 09:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-13 17:34
Articles in Press
2018-12-13 17:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-12-17 23:20
Typeset the Manuscript
2018-12-26 03:09
Publish the Manuscript Online
2018-12-27 08:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Study
Article Title Safety of hepatitis B virus core antigen-positive grafts in liver transplantation: A single-center experience in China
Manuscript Source Unsolicited Manuscript
All Author List Ming Lei, Lu-Nan Yan, Jia-Yin Yang, Tian-Fu Wen, Bo Li, Wen-Tao Wang, Hong Wu, Ming-Qing Xu, Zhe-Yu Chen and Yong-Gang Wei
Author(s) ORCID Number
Ming Lei http://orcid.org/0000-0001-7103-5700
Lu-Nan Yan http://orcid.org/0000-0003-3603-3595
Jia-Yin Yang http://orcid.org/0000-0003-2299-9188
Tian-Fu Wen http://orcid.org/0000-0003-4668-4455
Bo Li http://orcid.org/0000-0002-2124-7163
Wen-Tao Wang http://orcid.org/0000-0002-9176-2718
Hong Wu http://orcid.org/0000-0002-6329-2202
Ming-Qing Xu http://orcid.org/0000-0003-2442-5524
Zhe-Yu Chen http://orcid.org/0000-0003-3506-0823
Yong-Gang Wei http://orcid.org/0000-0003-0428-8366
Funding Agency and Grant Number
Corresponding Author Lu-Nan Yan, MD, Professor, Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, 37 Guoxuexiang, Chengdu 610041, Sichuan Province, China. yanlunan688@126.com
Key Words Liver transplantation; Long-term outcome; Hepatitis B core antibody; Hepatitis B virus infection
Core Tip Considering the shortage of suitable liver grafts for liver transplantation, using hepatitis B virus core antibody positive (HBcAb+) livers might be a possible way to enlarge the donor pool. However, the safety is controversial and not widely evaluated in Chinese patients. Our retrospective study enrolling 1071 patients found that HBcAb+ grafts did not affect the long-term outcome. Although post-transplant hepatitis B virus (HBV) infection had a relatively higher incidence in HBV surface antigen-negative patients with such grafts, it did not affect patient and graft survival. We also found that sufficient anti-HBs titers in recipients might be a protective factor against de novo HBV infection. Combined with proper postoperative antiviral prophylaxis, utilization of HBcAb+ grafts is feasible.
Publish Date 2018-12-27 08:56
Citation Lei M, Yan LN, Yang JY, Wen TF, Li B, Wang WT, Wu H, Xu MQ, Chen ZY, Wei YG. Safety of hepatitis B virus core antigen-positive grafts in liver transplantation: A single-center experience in China. World J Gastroenterol 2018; 24(48): 5525-5536
Url https://www.wjgnet.com/1007-9327/full/v24/i48/5525.htm
DOI https://dx.doi.org/10.3748/wjg.v24.i48.5525
Full Article (PDF) WJG-24-5525.pdf
Full Article (Word) WJG-24-5525.docx
Manuscript File 43054-Review.docx
Answering Reviewers 43054-Answering reviewers.pdf
Audio Core Tip 43054-Audio core tip.mp3
Biostatistics Review Certificate 43054-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 43054-Conflict-of-interest statement.pdf
Copyright License Agreement 43054-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 43054-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 43054-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 43054-Language certificate.pdf
Supplementary Material 43054-Supplementary material.pdf
Peer-review Report 43054-Peer-review(s).pdf
Scientific Misconduct Check 43054-Scientific misconduct check.pdf
Scientific Editor Work List 43054-Scientific editor work list.pdf