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9/12/2014 8:41:00 PM | Browse: 904 | Download: 698
Publication Name World Journal of Gastroenterology
Manuscript ID 4356
Country/Territory Italy
Received
2013-06-28 10:02
Peer-Review Started
2013-06-28 15:52
To Make the First Decision
2013-07-05 18:35
Return for Revision
2013-07-31 10:47
Revised
2013-08-07 22:02
Second Decision
2013-08-29 07:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-08-29 10:13
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-09-08 01:19
Typeset the Manuscript
2013-10-29 11:32
Publish the Manuscript Online
2013-11-16 18:29
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Neuromodulation for fecal incontinence: An effective surgical intervention
Manuscript Source Invited Manuscript
All Author List Giuseppe Chiarioni, Olafur S Palsson, Corrado R Asteria and William E Whitehead
Funding Agency and Grant Number
Funding Agency Grant Number
National Institute of Diabetes and Digestive and Kidney Disease R01 DK031369
Corresponding Author Giuseppe Chiarioni, MD, Division of Gastroenterology of the University of Verona, Valeggio s/M Hospital, Azienda Ospedaliera Universitaria Integrata di Verona, 37067 Valeggio sul Mincio, Verona, Italy. chiarioni@tin.it
Key Words Fecal incontinence; Neuromodulation; Sacral nerve stimulation; Biofeedback; Anal sphincter
Core Tip This review summarizes the evidence for neuromodulation of fecal incontinence. Neuromodulation is effective for some patients with fecal incontinence of different etiology unknown mechanism; when analyzed by intent to treat analysis, the median responder rate is 59%. The most common serious adverse event is infection at the site of implant which occurs in about 3% of patients. Cost of treatment is high relative to conservative treatment and biofeedback but seems to be cost-effective when offset by gains in quality-adjusted years. Randomized controlled trials comparing neuromodulation with biofeedback therapy in fecal incontinence are advisable to tailor patients' management.
Publish Date 2013-11-16 18:29
Citation Chiarioni G, Palsson OS, Asteria CR, Whitehead WE. Neuromodulation for fecal incontinence: An effective surgical intervention. World J Gastroenterol 2013; 19(41): 7048-7054
URL http://www.wjgnet.com/1007-9327/full/v19/i41/7048.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i41.7048
Full Article (PDF) WJG-19-7048.pdf
Manuscript File 4356-Review.docx
Answering Reviewers 4356-Answering reviewers.pdf
Copyright License Agreement 4356-Copyright assignment.pdf
Peer-review Report 4356-Peer review(s).pdf
Scientific Editor Work List 4356-Scientific editor work list.doc