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7/6/2019 11:29:12 AM | Browse: 66 | Download: 35
Publication Name World Journal of Clinical Cases
Manuscript ID 45588
Country of Manuscript Source China
2019-01-07 00:37
Peer-Review Started
2019-01-07 09:41
To Make the First Decision
2019-02-20 01:05
Return for Revision
2019-02-20 01:44
2019-04-04 02:01
Second Decision
2019-04-30 10:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-02 17:29
Articles in Press
2019-05-02 17:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-05-23 00:29
Typeset the Manuscript
2019-07-05 09:06
Publish the Manuscript Online
2019-07-06 11:29
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Medicine, Research and Experimental
Manuscript type Review
Article Title Role of the brain-gut axis in gastrointestinal cancer
Manuscript Source Unsolicited Manuscript
All Author List Yang-Zi Di, Bo-Sheng Han, Jun-Mao Di, Wei-Yan Liu and Qiang Tang
Author(s) ORCID Number
Yang-Zi Di http://orcid.org/0000-0002-9107-3808
Bo-Sheng Han http://orcid.org/0000-0003-3475-6562
Jun-Mao Di http://orcid.org/0000-0002-8854-7750
Qiang Tang http://orcid.org/0000-0002-2744-2015
Funding Agency and Grant Number
Correspondence To Qiang Tang, PhD, Chief Doctor, Doctor, Department of General Surgery, Shiyan Taihe Hospital, Hubei University of Medicine, Shiyan 442000, Hubei Province, China. tang_8q@126.com
Keywords Brain-gut axis; Gastrointestinal cancer; Neurotransmitters; Neuropeptides
Core Tip Although studies have revealed the role of the brain-gut-axis in cancer, the bidirectional signal transmission of the brain-gut-axis remains unclear. This review summarizes current findings concerning the relationship between the brain-gut axis and gastrointestinal (GI) cancer and focuses on the significant role of the brain-gut axis in tumorigenesis and cancer progression, including tumor proliferation, invasion, apoptosis, autophagy, and metastasis. The central nervous system, sympathetic or parasympathetic nervous systems, neurotransmitters, and neuropeptides may regulate the malignant tumor phenotype in GI cancers. An insight into these mechanisms may lead to the discovery of potential prognostic markers and new targets for GI cancer therapy.
Publish Date 2019-07-06 11:29
Citation Di YZ, Han BS, Di JM, Liu WY, Tang Q. Role of the brain-gut axis in gastrointestinal cancer. World J Clin Cases 2019; 7(13): 1554-1570
Url https://www.wjgnet.com/2307-8960/full/v7/i13/1554.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i13.1554
Full Article (PDF) WJCC-7-1554.pdf
Full Article (Word) WJCC-7-1554.docx
Manuscript File 45588-Review_Edited.rtf
Answering Reviewers 45588-Answering reviewers.pdf
Audio Core Tip 45588-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 45588-Conflict-of-interest statement.pdf
Copyright License Agreement 45588-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 45588-Language certificate.pdf
Peer-review Report 45588-Peer-review(s).pdf
Scientific Misconduct Check 45588-Scientific misconduct check.pdf
Scientific Editor Work List 45588-Scientific editor work list.pdf