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9/11/2014 8:39:00 PM | Browse: 418 | Download: 438
Publication Name World Journal of Gastroenterology
Manuscript ID 4560
Country/Territory Turkey
Received
2013-07-08 08:36
Peer-Review Started
2013-07-08 14:28
To Make the First Decision
2013-07-26 18:39
Return for Revision
2013-08-06 10:31
Revised
2013-09-01 19:30
Second Decision
2013-09-16 17:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-17 06:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-12-08 15:27
Publish the Manuscript Online
2014-01-20 16:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Autobiography
Article Title Serum concentrations of insulin-like growth factor-binding protein 5 in Crohn's disease
Manuscript Source Invited Manuscript
All Author List Gupse Adali, Elif Yorulmaz, Seyma Ozkanli, Celal Ulasoglu, Baris Bayraktar, Alev Orhun, Yasar Colak and Ilyas Tuncer
Funding Agency and Grant Number
Corresponding author Gupse Adali, MD, Department of Gastroenterology, Goztepe Training and Research Hospital, Istanbul Medeniyet University, Doktor Erkin Caddesi Kadikoy, Istanbul 34730, Turkey. gupseadali@gmail.com
Keywords Crohn's disease; Insulin-like growth factor-binding protein 5; Stricture; Immunohistochemistry; Enzyme-linked immunosorbent assay
Core Tip Previous studies have suggested that insulin-like growth factors are important for the growth and development of visceral smooth muscle. In particular, increased insulin-like growth factor-binding protein 5 expression has been described in inflamed and fibrotic intestinal tissue. In this study, we aim to investigate the possible role of insulin-like growth factor-binding protein 5 in Crohn's disease with stricture involvement. Crohn's disease patients had lower serum levels of IGFBP-5 compared to healthy controls. The results of the study suggest that additional research is necessary to explain the low circulating levels of IGFBP-5 in Crohn's disease patients.
Publish Date 2014-01-20 16:41
Citation Adali G, Yorulmaz E, Ozkanli S, Ulasoglu C, Bayraktar B, Orhun A, Colak Y, Tuncer I. Serum concentrations of insulin-like growth factor-binding protein 5 in Crohn’s disease. World J Gastroenterol 2013; 19(47): 9049-9056
Url http://www.wjgnet.com/1007-9327/full/v19/i47/9049.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i47.9049
Full Article (PDF) WJG-19-9049.pdf
Manuscript File 4560-Review.doc
Answering Reviewers 4560-Answering reviewers.pdf
Copyright License Agreement 4560-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate 4560-Language certificate.doc
Peer-review Report 4560-Peer reviewer(s).pdf
Scientific Editor Work List 4560-Scientific editor work list.doc