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8/7/2019 7:09:17 AM | Browse: 71 | Download: 37
Publication Name World Journal of Gastroenterology
Manuscript ID 45807
Country of Manuscript Source France
2019-01-17 01:44
Peer-Review Started
2019-01-18 04:09
To Make the First Decision
2019-01-31 07:03
Return for Revision
2019-01-31 08:32
2019-02-07 09:22
Second Decision
2019-02-22 09:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-02-23 05:13
Articles in Press
2019-02-23 05:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-08-05 08:09
Publish the Manuscript Online
2019-08-07 07:09
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Management of skin toxicities during panitumumab treatment in metastatic colorectal cancer
Manuscript Source Unsolicited Manuscript
All Author List Olivier Bouche, Meher Ben Abdelghani, Jean-Luc Labourey, Simon TRIBY, René-Jean Bensadoun, Thomas Jouary and Gaétan Des Guetz
Author(s) ORCID Number
Olivier Bouche http://orcid.org/0000-0002-8284-3743
Meher Ben Abdelghani http://orcid.org/0000-0003-2512-4272
Jean-Luc Labourey http://orcid.org/0000-0002-7453-1352
Simon TRIBY http://orcid.org/0000-0002-2980-178X
René-Jean Bensadoun http://orcid.org/0000-0003-1290-7497
Thomas Jouary http://orcid.org/0000-0002-9080-3661
Gaétan Des Guetz http://orcid.org/0000-0001-96436877
Funding Agency and Grant Number
Funding Agency Grant Number
Amgen 20090656 POPEC
Corresponding author Olivier Bouche, MD, Professor, Department of Gastroenterology and Digestive Oncology, Hôpital Robert Debré, CHU Reims, Avenue du Général Koenig, Reims 51092, France. obouche@chu-reims.fr
Keywords Metastatic colorectal cancer; Epidermal growth factor receptor inhibitors; Panitumumab; Skin toxicity; Quality of life;
Core Tip Anti-epidermal growth factor receptor therapy is associated with skin adverse events not previously reported with conventional chemotherapy. Prophylactic actions are recommended, but routine clinical management of these toxicities and their impact on quality of life remain unknown. This observational study describes a cohort of patients who began treatment with panitumumab for metastatic colorectal cancer. The rates of the different skin toxicities peaked at various times and were improved at the end of the follow-up. Nevertheless, their clinical management could be optimized with a better adherence to current recommendations. The impact of skin toxicities on patient’s quality of life appeared to be limited.
Publish Date 2019-08-07 07:09
Citation Bouché O, Ben Abdelghani M, Labourey JL, Triby S, Bensadoun RJ, Jouary T, Des Guetz G. Management of skin toxicities during panitumumab treatment in metastatic colorectal cancer. World J Gastroenterol 2019; 25(29): 4007-4018
Url https://www.wjgnet.com/1007-9327/full/v25/i29/4007.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i29.4007
Full Article (PDF) WJG-25-4007.pdf
Full Article (Word) WJG-25-4007.docx
Manuscript File 45807-Review.docx
Answering Reviewers 45807-Answering reviewers.pdf
Audio Core Tip 45807-Audio core tip.mp3
Biostatistics Review Certificate 45807-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 45807-Conflict-of-interest statement.pdf
Copyright License Agreement 45807-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 45807-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 45807-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 45807-Institutional review board statement.pdf
Peer-review Report 45807-Peer-review(s).pdf
Scientific Misconduct Check 45807-Scientific misconduct check.pdf
Scientific Editor Work List 45807-Scientific editor work list.pdf