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5/20/2019 9:05:35 AM | Browse: 413 | Download: 580
Publication Name World Journal of Gastroenterology
Manuscript ID 46489
Country/Territory China
Received
2019-02-14 07:59
Peer-Review Started
2019-02-17 09:33
To Make the First Decision
2019-03-20 06:45
Return for Revision
2019-03-21 07:22
Revised
2019-03-29 05:26
Second Decision
2019-04-19 07:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-04-20 02:02
Articles in Press
2019-04-20 02:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-04-24 13:16
Typeset the Manuscript
2019-05-20 00:46
Publish the Manuscript Online
2019-05-20 09:05
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Control Study
Article Title Risk factors for progression to acute-on-chronic liver failure during severe acute exacerbation of chronic hepatitis B virus infection
Manuscript Source Unsolicited Manuscript
All Author List Ling Yuan, Bai-Mei Zeng, Lu-Lu Liu, Yi Ren, Yan-Qing Yang, Jun Chu, Ying Li, Fang-Wan Yang, Yi-Huai He and Shi-De Lin
ORCID
Author(s) ORCID Number
Ling Yuan http://orcid.org/0000-0003-3457-8604
Bai-Mei Zeng http://orcid.org/0000-0003-4313-8686
Lu-Lu Liu http://orcid.org/0000-0003-1286-7632
Yi Ren http://orcid.org/0000-0001-5770-0460
Yan-Qing Yang http://orcid.org/0000-0002-9985-8677
Jun Chu http://orcid.org/0000-0002-8106-6305
Ying Li http://orcid.org/0000-0001-5793-5104
Fang-Wan Yang http://orcid.org/0000-0002-8227-7577
Yi-Huai He http://orcid.org/0000-0002-8639-3436
Shi-De Lin http://orcid.org/0000-0001-8803-4069
Funding Agency and Grant Number
Funding Agency Grant Number
the Funds of Chinese National Natural Science Foundation Project 81460124
Corresponding Author Shi-De Lin, MD, Chief Doctor, Occupational Physician, Professor, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, 201 Dalian street, Zunyi 563003, Guizhou Province, China. linshide6@zmc.edu.cn
Key Words Acute-on-chronic liver failure; Chronic hepatitis B; Hepatic decompensation; Liver cirrhosis; Risk factors; Severe acute exacerbation
Core Tip The risk factors related to progression in patients with severe acute exacerbation (SAE) of chronic hepatitis B virus (HBV) infection remain unknown. This is the largest study to identify the risk factors related to progression to hepatic decompensation (HD) and acute-on-chronic liver failure (ACLF) in compensated patients with SAE of chronic HBV infection. We found liver cirrhosis is an independent risk factor for progression to both HD and ACLF. High model for end-stage liver disease score, high aspartate aminotransferase, and low prothrombin activity are associated with progression to ACLF.
Publish Date 2019-05-20 09:05
Citation Yuan L, Zeng BM, Liu LL, Ren Y, Yang YQ, Chu J, Li Y, Yang FW, He YH, Lin SD. Risk factors for progression to acute-on-chronic liver failure during severe acute exacerbation of chronic hepatitis B virus infection. World J Gastroenterol 2019; 2019; 25(19): 2327-2337
URL https://www.wjgnet.com/1007-9327/full/v25/i19/2327.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i19.2327
Full Article (PDF) WJG-25-2327.pdf
Full Article (Word) WJG-25-2327.docx
Manuscript File 46489-Review_Edited.docx
Answering Reviewers 46489-Answering reviewers.pdf
Audio Core Tip 46489-Audio core tip.mp3
Biostatistics Review Certificate 46489-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 46489-Conflict-of-interest statement.pdf
Copyright License Agreement 46489-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46489-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 46489-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 46489-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 46489-Language certificate.pdf
Peer-review Report 46489-Peer-review(s).pdf
Scientific Misconduct Check 46489-Scientific misconduct check.pdf
Scientific Editor Work List 46489-Scientific editor work list.pdf