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Articles Published Processes
4/25/2019 3:13:57 AM | Browse: 685 | Download: 1008
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Received |
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2019-02-20 01:42 |
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Peer-Review Started |
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2019-02-20 03:09 |
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To Make the First Decision |
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2019-03-14 06:50 |
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Return for Revision |
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2019-03-14 07:00 |
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Revised |
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2019-03-21 11:55 |
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Second Decision |
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2019-03-22 09:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-03-25 04:32 |
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Articles in Press |
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2019-03-25 04:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-04-03 05:41 |
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Typeset the Manuscript |
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2019-04-19 04:10 |
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Publish the Manuscript Online |
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2019-04-25 03:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Role and mechanism of circ-PRKCI in hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Su-Xia Qi, Hui Sun, Hui Liu, Jing Yu, Zhi-Yong Jiang and Ping Yan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ping Yan, MSc, Attending Doctor, Emergency Department, Qingdao Municipal Hospital (Group), No. 5 Donghai Middle Road, Qingdao 266000, Shandong Province, China. kschdje384@163.com |
| Key Words |
Circ-PRKCI; Hepatocellular carcinoma; Cell invasion; Protein kinase B signaling pathway; Progression |
| Core Tip |
The circular RNA circ-PRKCI plays an important role in a variety of digestive system tumors. This study explored the role and mechanism of circ-PRKCI in hepatocellular carcinoma. The results of the study showed that: (1) significant high circ-PRKCI expression is present in liver cancer progression; (2) circ-PRKCI promotes the invasion of liver cancer cells; (3) circ-PRKCI can function as a ceRNA to regulate protein kinase B signaling pathway along with miRNA-545; and (4) circ-PRKCI target gene E2F7 may affect the survival and prognosis of patients with liver cancer. This study provides a new research direction and theoretical basis for the treatment of HCC. |
| Publish Date |
2019-04-25 03:13 |
| Citation |
Qi SX, Sun H, Liu H, Yu J, Jiang ZY, Yan P. Role and mechanism of circ-PRKCI in hepatocellular carcinoma. World J Gastroenterol 2019; 25(16): 1964-1974 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i16/1964.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i16.1964 |
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