Publication Name	World Journal of Stem Cells
Manuscript ID	46673
Country	Italy

Received	2019-02-20 04:05
Peer-Review Started	2019-02-20 06:03
To Make the First Decision	2019-04-16 06:30
Return for Revision	2019-04-17 08:49
Revised	2019-05-28 06:30
Second Decision	2019-05-29 01:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-06-13 02:52
Articles in Press	2019-06-13 02:52
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-07-13 18:46
Typeset the Manuscript	2019-08-22 12:11
Publish the Manuscript Online	2019-08-26 10:16

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Orchestrating stem cell fate: Novel tools for regenerative medicine
Manuscript Source	Invited Manuscript
All Author List	Sara Cruciani, Sara Santaniello, Andrea Montella, Carlo Ventura and Margherita Maioli
ORCID	Author(s) ORCID Number Sara Cruciani http://orcid.org/0000-0001-8632-2577 Sara Santaniello http://orcid.org/0000-0003-0805-0478 Andrea Montella http://orcid.org/0000-0002-5514-4453 Carlo Ventura http://orcid.org/0000-0001-9333-0321 Margherita Maioli http://orcid.org/0000-0003-0187-4968
Funding Agency and Grant Number
Corresponding Author	Margherita Maioli, PhD, Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43/B, Sassari 07100, Italy. mmaioli@uniss.it
Key Words	Stem cells; Epigenetics; Self-renewal; In vitro differentiation; Physical stimuli; Stem cell fate
Core Tip	Latest advances in the field of stem cells concern epigenetics and its role in self-renewal and differentiation capability. Activation or silencing of genes controlling stemness and tissue-lineage specification are related to chromatin-remodeling factors and epigenetic regulators. In this review, we focused on the principal epigenetic markers that regulate stem cell pluripotency, in vitro manipulation and the current state-of-the-art of human mesenchymal stem cells in vivo applications.
Publish Date	2019-08-26 10:16
Citation	Cruciani S, Santaniello S, Montella A, Ventura C, Maioli M. Orchestrating stem cell fate: Novel tools for regenerative medicine. World J Stem Cells 2019; 11(8):464-475
URL	https://www.wjgnet.com/1948-0210/full/v11/i8/464.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i8.464

Full Article (PDF)	WJSC-11-464.pdf
Full Article (Word)	WJSC-11-464.docx
Manuscript File	FP6897_de26_CE1MS-edit2.docx
Answering Reviewers	46673-Answering reviewers.pdf
Audio Core Tip	46673-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	46673-Conflict-of-interest statement.pdf
Copyright License Agreement	46673-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	46673-Language certificate.pdf
Peer-review Report	46673-Peer-review(s).pdf
Scientific Misconduct Check	46673-Scientific misconduct check.pdf
Scientific Editor Work List	46673-Scientific editor work list.pdf