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6/26/2019 11:43:52 AM | Browse: 818 | Download: 1090
Publication Name World Journal of Stem Cells
Manuscript ID 46685
Country/Territory Spain
Received
2019-02-23 06:10
Peer-Review Started
2019-02-26 00:25
To Make the First Decision
2019-03-18 06:29
Return for Revision
2019-03-22 01:30
Revised
2019-04-03 11:01
Second Decision
2019-04-30 08:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-06 02:04
Articles in Press
2019-05-06 02:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-06-24 10:27
Publish the Manuscript Online
2019-06-26 11:43
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Minireviews
Article Title Effect of aging on behaviour of mesenchymal stem cells
Manuscript Source Invited Manuscript
All Author List Juan Fafián-Labora, Miriam Morente-López and María C Arufe
ORCID
Author(s) ORCID Number
Juan Fafián-Labora http://orcid.org/0000-0003-1510-8666
Miriam Morente-López http://orcid.org/0000-0001-8547-7489
María C Arufe http://orcid.org/0000-0003-3725-0743
Funding Agency and Grant Number
Funding Agency Grant Number
Xunta de Galicia
Corresponding Author María C Arufe, PhD, Professor, Grupo de Terapia Celular y Medicina Regenerativa, Departamento de Fisioterapia, Ciencias Biomédicas y Medicina, Universidade da Coruña, Facultad de Ciencias de la Salud, Campus de Oza, INIBIC-CHUAC, A Coruña 15006, Spain. maria.arufe@udc.es
Key Words Mesenchymal stem cells; Aging; Autophagy; Mitochondrial stress; Extracellular vesicles
Core Tip The point of interest of this work is the behaviour of the mesenchymal stromal cell (MSC) through aging, which can occur over time in the culture (in vitro) or in its own physiological niche (in vivo). This review defines the current knowledge published in the MSC field that focuses mainly on the mechanisms that influence its senescence in vivo and in vitro in the last three years. Three cellular mechanisms are of special importance in this review, since they can decisively influence the behaviour of MSC in aging, such as autophagy, oxidative stress and the production of extracellular vesicles.
Publish Date 2019-06-26 11:43
Citation Fafián-Labora JA, Morente-López M, Arufe MC. Effect of aging on behaviour of mesenchymal stem cells. World J Stem Cells 2019; 11(6): 337-346
URL https://www.wjgnet.com/1948-0210/full/v11/i6/337.htm
DOI https://dx.doi.org/10.4252/wjsc.v11.i6.337
Full Article (PDF) WJSC-11-337.pdf
Full Article (Word) WJSC-11-337.docx
Manuscript File 46685-Review.doc
Answering Reviewers 46685-Answering reviewers.pdf
Audio Core Tip 46685-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 46685-Conflict-of-interest statement.pdf
Copyright License Agreement 46685-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46685-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 46685-Language certificate.pdf
Peer-review Report 46685-Peer-review(s).pdf
Scientific Editor Work List 46685-Scientific editor work list.pdf