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9/29/2019 10:56:48 AM | Browse: 38 | Download: 25
Publication Name World Journal of Clinical Cases
Manuscript ID 47019
Country of Manuscript Source Italy
Received
2019-03-27 01:28
Peer-Review Started
2019-03-28 08:31
To Make the First Decision
2019-04-18 07:00
Return for Revision
2019-05-13 03:26
Revised
2019-07-25 15:36
Second Decision
2019-07-27 02:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-07-27 22:12
Articles in Press
2019-07-27 22:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-08-08 16:56
Typeset the Manuscript
2019-09-23 00:49
Publish the Manuscript Online
2019-09-29 10:56
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Medicine, Research and Experimental
Manuscript Type Case Report
Article Title Successful multidisciplinary clinical approach and molecular characterization by whole transcriptome sequencing of a cardiac myxofibrosarcoma: A case report
Manuscript Source Unsolicited Manuscript
All Author List Maristella Saponara, Valentina Indio, Carmine Pizzi, Elena-Daniela Serban, Milena Urbini, Annalisa Astolfi, Pasquale Paolisso, Sofia Martin Suarez, Margherita Nannini, Davide Pacini, Valentina Agostini, Ornella Leone, Valentina Ambrosini, Giuseppe Tarantino, Stefano Fanti, Fabio Niro, Francesco Buia, Domenico Attina' and Maria Abbondanza Pantaleo
ORCID
Author(s) ORCID Number
Maristella Saponara http://orcid.org/0000-0003-0715-171X
Valentina Indio http://orcid.org/0000-0002-8854-3821
Carmine Pizzi http://orcid.org/0000-0002-4048-675X
Elena-Daniela Serban http://orcid.org/0000-0002-2600-614X
Milena Urbini http://orcid.org/0000-0002-3364-9098
Annalisa Astolfi http://orcid.org/0000-0002-2732-0747
Pasquale Paolisso http://orcid.org/0000-0002-7017-778X
Sofia Martin Suarez http://orcid.org/0000-0003-4627-4958
Margherita Nannini http://orcid.org/0000-0002-2103-1960
Davide Pacini http://orcid.org/0000-0002-4298-3792
Valentina Agostini http://orcid.org/0000-0001-5540-2371
Ornella Leone http://orcid.org/0000-0001-6412-3294
Valentina Ambrosini http://orcid.org/0000-0002-5008-5351
Giuseppe Tarantino http://orcid.org/0000-0002-6078-6856
Stefano Fanti http://orcid.org/0000-0003-1486-2624
Fabio Niro http://orcid.org/0000-0001-9696-1022
Francesco Buia http://orcid.org/0000-0002-8038-6788
Domenico Attina' http://orcid.org/0000-0001-6055-5313
Maria Abbondanza Pantaleo http://orcid.org/0000-0002-0177-6957
Funding Agency and Grant Number
Corresponding author Maristella Saponara, MD, Academic Research, Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, Bologna 40138, Bologna, Italy. maristella.saponara@unibo.it
Keywords Cardiac sarcoma; Myxofibrosarcoma; Whole transcriptome sequencing; Doxorubicin; Gemcitabine; Case report
Core Tip We present the case of an elderly woman affected by myxofibrosarcoma of the left atrium, a rare histotype of cardiac sarcoma. She underwent surgery, but, unfortunately, disease recurred. Therefore, she started first and second line chemotherapy with doxorubicin and then gemcitabine, obtaining good and durable radiologic response and complete metabolic response. Accurate histologic description is reported and molecular characterization of the tumor, by whole transcriptome sequencing, is also encompassed in order to better characterize this rare cancer and possibly identify pathognomonic molecular events or gene expression profiles shared with other sarcomas amenable for targeted medical therapy.
Publish Date 2019-09-29 10:56
Citation Saponara M, Indio V, Pizzi C, Serban E, Urbini M, Astolfi A, Paolisso P, Suarez SM, Nannini M, Pacini D, Agostini V, Leone O, Ambrosini V, Tarantino G, Fanti S, Niro F, Buia F, AttinàD, Pantaleo MA. Successful multidisciplinary clinical approach and molecular characterization by whole transcriptome sequencing of a cardiac myxofibrosarcoma: A case report. World J Clin Cases 2019; 7(19):3018-3026
Url https://www.wjgnet.com/2307-8960/full/v7/i19/3018.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i19.3018
Full Article (PDF) WJCC-7-3018.pdf
Full Article (Word) WJCC-7-3018.docx
Manuscript File FP6951_ce25_CE1MS-edit2-MS.docx
Answering Reviewers 47019-Answering reviewers.pdf
Audio Core Tip 47019-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 47019-Conflict-of-interest statement.pdf
Copyright License Agreement 47019-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 47019-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 47019-Language certificate.pdf
Video 47019-Video core tip.wmv
Supplementary Material 47019-Supplementary material.pdf
Peer-review Report 47019-Peer-review(s).pdf
Scientific Misconduct Check 47019-Scientific misconduct check.pdf
Scientific Editor Work List 47019-Scientific editor work list.pdf