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6/21/2019 3:42:23 AM | Browse: 258 | Download: 221
Publication Name World Journal of Gastroenterology
Manuscript ID 47141
Country/Territory China
Received
2019-03-07 02:10
Peer-Review Started
2019-03-07 06:28
To Make the First Decision
2019-04-08 00:43
Return for Revision
2019-04-08 07:02
Revised
2019-04-17 13:42
Second Decision
2019-04-28 09:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-04-29 10:17
Articles in Press
2019-04-29 10:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-05-04 22:56
Typeset the Manuscript
2019-06-19 05:46
Publish the Manuscript Online
2019-06-21 03:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Field of Vision
Article Title Modified FOLFIRINOX for resected pancreatic cancer: Opportunities and challenges
Manuscript Source Invited Manuscript
All Author List Feng Yang, Chen Jin, De-Liang Fu and Andrew L Warshaw
ORCID
Author(s) ORCID Number
Feng Yang http://orcid.org/0000-0001-8790-6072
Chen Jin http://orcid.org/0000-0002-4330-9716
De-Liang Fu http://orcid.org/0000-0003-4060-8101
Andrew L Warshaw http://orcid.org/0000-0001-7788-3110
Funding Agency and Grant Number
Funding Agency Grant Number
National Key R&D Program of China 2017YFC1308604
Corresponding author Feng Yang, MD, PhD, Associate Professor, Surgeon, Surgical Oncologist, Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Central Urumqi Road, Shanghai 200040, China. yffudan98@126.com
Key Words Pancreatic cancer; Adjuvant therapy; FOLFIRINOX; Neutrophil-to-lymphocyte; Nanoliposomal irinotecan
Core Tip Adjuvant chemotherapy for pancreatic cancer has been developed based on the experiences made with palliative chemotherapy. Nevertheless, the optimal regimen remains controversial. The Partenariat de Recherche en Oncologie Digestive 24 trial showed an impressive benefit of modified FOLFIRINOX over gemcitabine alone. The remarkable results mark a new milestone in treating resectable pancreatic cancer and have now changed the standard of care. Here, we discussed an issue of difference between this trial and previous phase III trials, as well as potential biomarkers predicting therapeutic response. Several ongoing trials of replacing part of the FOLFIRINOX regimen with other drugs for pancreatic cancer were summarized.
Publish Date 2019-06-21 03:42
Citation Yang F, Jin C, Fu DL, Warshaw AL. Modified FOLFIRINOX for resected pancreatic cancer: Opportunities and challenges. World J Gastroenterol 2019; 25(23): 2839-2845
Url https://www.wjgnet.com/1007-9327/full/v25/i23/2839.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i23.2839
Full Article (PDF) WJG-25-2839.pdf
Manuscript File 47141-Review_Edited.doc
Answering Reviewers 47141-Answering reviewers.pdf
Audio Core Tip 47141-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 47141-Conflict-of-interest statement.pdf
Copyright License Agreement 47141-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 47141-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 47141-Language certificate.pdf
Peer-review Report 47141-Peer-review(s).pdf
Scientific Misconduct Check 47141-Google-MA RY-1.png
Scientific Misconduct Check 47141-Google-MA RY-2.png
Scientific Misconduct Check 47141-Scientific misconduct check.pdf
Scientific Editor Work List 47141-Scientific editor work list.pdf