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Publication Name World Journal of Hepatology
Manuscript ID 4745
Country/Territory Turkey
Received
2013-07-20 09:33
Peer-Review Started
2013-07-22 19:45
To Make the First Decision
2013-07-26 18:38
Return for Revision
2013-07-29 20:49
Revised
Second Decision
2013-10-11 14:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-10-12 00:38
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-10-22 14:25
Typeset the Manuscript
2013-11-06 15:23
Publish the Manuscript Online
2013-11-26 22:03
ISSN 1948-5182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Genetics and Heredity
Manuscript Type Autobiography
Article Title Increased bone mineral density in patients with non-alcoholic steatohepatitis
Manuscript Source Invited Manuscript
All Author List Muhsin Kaya, Devran Işık, Remzi Beştaş, Osman Evliyaoğlu, Veysi Akpolat, Hüseyin Büyükbayram and Mehmet Ali Kaplan
Funding Agency and Grant Number
Corresponding Author Muhsin Kaya, MD, Department of Gastroenterology, Dicle University, School of Medicine, Diyarbakır 21100, Turkey. muhsinkaya20@hotmail.com
Key Words Non-alcoholic steatohepatitis; Hepatic osteodystrophy; Bone mineral density
Core Tip Identifying the relationship between non-alcoholic steatohepatitis and bone mineral density (BMD) and its underlying mechanism is important. We found that patients with biopsy-proven non-alcoholic steatohepatitis (NASH) had higher lumbar BMD and serum 25-OH-vitamin-D3 levels compared to healthy controls. We did not find a significant relationship between serum levels of thyroid hormones, sex hormones, parathormone and cytokines, such as tumor necrosis factor-α, interleukin-1 (IL-1), IL-6, insulin-like growth factor-1, IGFBP-3 levels and BMD. An elevated serum 25-OH-vitamin D3 level may be the principle responsible factor in the increased bone mineral density in patients with NASH.
Publish Date 2013-11-26 22:03
Citation Kaya M, I??k D, Be?ta? R, Evliyao?lu O, Akpolat V, Büyükbayram H, Kaplan MA. Increased bone mineral density in patients with non-alcoholic steatohepatitis. World J Hepatol 2013; 5(11): 627-634
URL http://www.wjgnet.com/1948-5182/full/v5/i11/627.htm
DOI http://dx.doi.org/10.4254/wjh.v5.i11.627
Full Article (PDF) WJH-5-627.pdf
Manuscript File 4745-Review.doc
Answering Reviewers 4745-Answering reviewers.pdf
Copyright License Agreement 4745-Copyright assignment.pdf
Peer-review Report 4745-Peer review(s).pdf
Scientific Editor Work List 4745-Scientific editor work list.doc