| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Seasonal variations in the onset of ulcerative colitis in Japan
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Shigeo Koido, Toshifumi Ohkusa, Hiroaki Saito, Tetsuji Yokoyama, Tomoyoshi Shibuya, Naoto Sakamoto, Kan Uchiyama, Hiroshi Arakawa, Taro Osada, Akihito Nagahara, Sumio Watanabe and Hisao Tajiri |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Grants in Aid for Scientific Research (C) from the Japanese Ministry of Education, Culture, Sports, Science, and Technology |
23501289 |
|
| Corresponding Author |
Shigeo Koido, MD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, the Jikei University School of Medicine, 8 Chome-3-1 Kokuryocho, Chiba 277-8564, Japan. shigeo_koido@jikei.ac.jp |
| Key Words |
Japanese population; Onset; Relapse; Seasonal variations; Ulcerative colitis |
| Core Tip |
Monthly seasonality in the symptomatic onset of ulcerative colitis (UC) during October and March was observed in Japan. The onset of symptoms frequently occurred during the winter, whereas relapse of UC particularly occurred in October. Upper respiratory inflammation was one of the main factors responsible for relapse. Therefore, environmental factors associated with winter and spring seasonality may be responsible for triggering the clinical onset of UC in Japan. |
| Publish Date |
2014-01-20 16:41 |
| Citation |
Koido S, Ohkusa T, Saito H, Yokoyama T, Shibuya T, Sakamoto N, Uchiyama K, Arakawa H, Osada T, Nagahara A, Watanabe S, Tajiri H. Seasonal variations in the onset of ulcerative colitis in Japan. World J Gastroenterol 2013; 19(47): 9063-9068 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i47/9063.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i47.9063 |
