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8/14/2019 1:31:33 PM | Browse: 637 | Download: 829
Publication Name World Journal of Gastroenterology
Manuscript ID 47633
Country/Territory Romania
Received
2019-04-01 01:08
Peer-Review Started
2019-04-02 00:15
To Make the First Decision
2019-04-30 10:30
Return for Revision
2019-05-05 03:45
Revised
2019-07-12 19:04
Second Decision
2019-07-19 09:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-07-19 16:02
Articles in Press
2019-07-19 16:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-08-14 07:09
Publish the Manuscript Online
2019-08-14 13:31
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions
Manuscript Source Invited Manuscript
All Author List Anca Negovan, Mihaela Iancu, Emoke Fulop and Claudia Banescu
ORCID
Author(s) ORCID Number
Anca Negovan http://orcid.org/0000-0003-2115-6576
Mihaela Iancu http://orcid.org/0000-0002-4557-5364
Emoke Fulop http://orcid.org/0000-0002-9973-0454
Claudia Banescu http://orcid.org/0000-0002-3235-524X
Funding Agency and Grant Number
Funding Agency Grant Number
Internal Research Grant from the University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureș 615/12/17.01.2019
Corresponding Author Mihaela Iancu, MSc, PhD, Lecturer, Department of Medical Informatics and Biostatistics, University of Medicine and Pharmacy "Iuliu Hațieganu", Louis Pasteur, Cluj-Napoca 400349, Romania. miancu@umfcluj.ro
Key Words Helicobacter pylori; Gastritis; Premalignant; Glandular atrophy; Intestinal metaplasia; Single-nuclear polymorphism
Core Tip The role of cytokines and their gene variants has been questioned in relation to Helicobacter pylori (H. pylori) gastritis and gastric cancer but only infrequently for preneoplastic lesions. To date, only the single nucleotide polymorphisms IL-10T-819C, IL-8-251, IL-18RAP917997, IL-22 rs1179251, IL1-B-511, IL1-B-3954, IL4R-398 and IL1RN appear to be predictors for premalignant gastric lesion susceptibility. In order to develop preventative strategies, further studies using multivariable models to test the modifying effect of H. pylori infection on the relationship between cytokine gene variants and premalignant lesions or to test the interaction between H. pylori and cytokine gene variants should be considered.
Publish Date 2019-08-14 13:31
Citation Negovan A, Iancu M, Fülöp E, Bănescu C. Helicobacter pylori and cytokine gene variants as predictors of premalignant gastric lesions. World J Gastroenterol 2019; 25(30): 4105-4124
URL https://www.wjgnet.com/1007-9327/full/v25/i30/4105.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i30.4105
Full Article (PDF) WJG-25-4105.pdf
Full Article (Word) WJG-25-4105.docx
Manuscript File 47633-Review.docx
Answering Reviewers 47633-Answering reviewers.pdf
Audio Core Tip 47633-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 47633-Conflict-of-interest statement.pdf
Copyright License Agreement 47633-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 47633-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 47633-Language certificate.pdf
Peer-review Report 47633-Peer-review(s).pdf
Scientific Misconduct Check 47633-Bing-Yan JP-1.jpg
Scientific Misconduct Check 47633-Scientific misconduct check.pdf
Scientific Editor Work List 47633-Scientific editor work list.pdf