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8/7/2019 7:09:17 AM | Browse: 78 | Download: 64
Publication Name World Journal of Gastroenterology
Manuscript ID 47869
Country of Manuscript Source Thailand
2019-03-29 01:06
Peer-Review Started
2019-03-29 03:29
To Make the First Decision
2019-06-10 08:17
Return for Revision
2019-06-14 02:24
2019-06-21 09:23
Second Decision
2019-07-05 10:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-07-05 23:46
Articles in Press
2019-07-05 23:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-08-05 08:38
Publish the Manuscript Online
2019-08-07 07:09
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Honokiol-enhanced cytotoxic T lymphocyte activity against cholangiocarcinoma cells mediated by dendritic cells pulsed with damage-associated molecular patterns
Manuscript Source Unsolicited Manuscript
All Author List Arunya Jiraviriyakul, Worawat Songjang, Pongsathorn Kaewthet, Phachsita Tanawatkitichai, Punyapat Bayan and Sutatip Pongcharoen
Author(s) ORCID Number
Arunya Jiraviriyakul http://orcid.org/0000-0003-0122-5984
Worawat Songjang http://orcid.org/0000-0002-7799-2947
Pongsathorn Kaewthet http://orcid.org/0000-0003-1338-4288
Phachsita Tanawatkitichai http://orcid.org/0000-0002-4228-5302
Punyapat Bayan http://orcid.org/0000-0001-9040-5017
Sutatip Pongcharoen http://orcid.org/0000-0002-2415-9468
Funding Agency and Grant Number
Funding Agency Grant Number
Naresuan University R2559B102
Naresuan University R2562C012
Thailand Research Fund BRG6180010
Corresponding author Sutatip Pongcharoen, PhD, Associate Professor, Division of Immunology, Department of Medicine, Faculty of Medicine, Naresuan University, Tapho District, Muang, Meaung 65000, Phitsanulok, Thailand. sutatipp@nu.ac.th
Keywords Cholangiocarcinoma; Dendritic cells; Honokiol; Damage-associated molecular patterns; Tumor cell lysates;
Core Tip We constructed dendritic cells (DCs) loaded with cell lysates derived from honokiol-treated cholangiocarcinoma tumour cells, with the aim of eliciting apoptosis in tumour cells and creating a broad array of tumour associated antigents in the form of dead and dying cells. Our data demonstrated that honokiol-treated cholangiocacinoma cells-derived tumour cell lysates could improve the fuctions for effector T lymphocytes in killing of the cancer cells. This suggested that honokiol enhanced the immunogenicity of cholangiocarcinoma antigens with increased effectiveness of DC-based vaccine formulation.
Publish Date 2019-08-07 07:09
Citation Jiraviriyakul A, Songjang W, Kaewthet P, Tanawatkitichai P, Bayan P, Pongcharoen S. Honokiol-enhanced cytotoxic T lymphocyte activity against cholangiocarcinoma cells mediated by dendritic cells pulsed with damage-associated molecular pattern. World J Gastroenterol 2019; 25(29): 3941-3955
Url https://www.wjgnet.com/1007-9327/full/v25/i29/3941.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i29.3941
Full Article (PDF) WJG-25-3941.pdf
Full Article (Word) WJG-25-3941.docx
Manuscript File 47869-Review.docx
Answering Reviewers 47869-Answering reviewers.pdf
Audio Core Tip 47869-Audio core tip.aiff
Biostatistics Review Certificate 47869-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 47869-Conflict-of-interest statement.pdf
Copyright License Agreement 47869-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 47869-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 47869-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 47869-Language certificate.pdf
Supplementary Material 47869-Supplementary material.pdf
Peer-review Report 47869-Peer-review(s).pdf
Scientific Misconduct Check 47869-Scientific misconduct check.pdf
Scientific Editor Work List 47869-Scientific editor work list.pdf