BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/21/2019 3:42:23 AM | Browse: 718 | Download: 1311
Publication Name World Journal of Gastroenterology
Manuscript ID 48062
Country/Territory China
Received
2019-04-04 00:38
Peer-Review Started
2019-04-04 00:52
To Make the First Decision
2019-04-11 08:53
Return for Revision
2019-04-12 01:24
Revised
2019-04-27 04:58
Second Decision
2019-05-17 09:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-18 12:41
Articles in Press
2019-05-18 12:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-05-30 23:01
Typeset the Manuscript
2019-06-19 03:51
Publish the Manuscript Online
2019-06-21 03:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title NIMA related kinase 2 promotes gastric carcinoma cells proliferation via ERK/MAPK signaling
Manuscript Source Unsolicited Manuscript
All Author List Wei-Dong Fan, Tao Chen and Peng-Jun Liu
ORCID
Author(s) ORCID Number
Wei-Dong Fan http://orcid.org/0000-0002-8545-150X
Tao Chen http://orcid.org/0000-0001-5276-3913
Peng-Jun Liu http://orcid.org/0000-0002-6700-9072
Funding Agency and Grant Number
Corresponding Author Peng-Jun Liu, MD, Attending Doctor, Chief Doctor, Department of Gastroenterology, the Wujin Hospital Affiliated to Jiangsu University, No. 2 Yongning north Road, Changzhou 213002, Jiangsu Province, China. liupengjun800@163.com
Key Words NIMA related kinase 2; ERK/MAPK signaling; Cyclin D1; Cell proliferation; Gastric cancer
Core Tip Expression of NIMA related kinase 2 (NEK2) is significantly upregulated in human gastric cancer (GC) tissues and cells. Furthermore, combined NEK2 and ERK expressions may predict overall survival in patients with GC. Surprisingly, NEK2 regulates the expression of Cyclin D1 by affecting the phosphorylation of ERK and c-JUN in GC and mediates cell proliferation via ERK/c-JUN/Cyclin D1 axis.
Publish Date 2019-06-21 03:42
Citation Fan WD, Chen T, Liu PJ. NIMA related kinase 2 promotes gastric carcinoma cells proliferation via ERK/MAPK signaling. World J Gastroenterol 2019; 25(23): 2898-2910
URL https://www.wjgnet.com/1007-9327/full/v25/i23/2898.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i23.2898
Full Article (PDF) WJG-25-2898.pdf
Full Article (Word) WJG-25-2898.docx
Manuscript File 48062-Review_Edited.docx
Answering Reviewers 48062-Answering reviewers.pdf
Audio Core Tip 48062-Audio core tip.mp3
Biostatistics Review Certificate 48062-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 48062-Conflict-of-interest statement.pdf
Copyright License Agreement 48062-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 48062-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 48062-Language certificate.pdf
Peer-review Report 48062-Peer-review(s).pdf
Scientific Misconduct Check 48062-Google-MA RY-1.png
Scientific Misconduct Check 48062-Google-MA RY-2.png
Scientific Misconduct Check 48062-Scientific misconduct check.pdf
Scientific Editor Work List 48062-Scientific editor work list.pdf