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10/16/2019 12:17:24 PM | Browse: 28 | Download: 19
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 48065
Country of Manuscript Source Italy
Received
2019-04-19 01:40
Peer-Review Started
2019-04-22 00:12
To Make the First Decision
2019-06-05 06:39
Return for Revision
2019-06-06 03:03
Revised
2019-07-11 13:55
Second Decision
2019-09-04 08:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-05 03:19
Articles in Press
2019-09-05 03:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-11 20:08
Typeset the Manuscript
2019-10-14 09:34
Publish the Manuscript Online
2019-10-16 12:17
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Oncology
Manuscript Type Review
Article Title Precision medicine in gastric cancer
Manuscript Source Invited Manuscript
All Author List Patrizia Bonelli, Antonella Borrelli, Franca Maria Tuccillo, Lucrezia Silvestro, Raffaele Palaia and Franco Maria Buonaguro
ORCID
Author(s) ORCID Number
Patrizia Bonelli http://orcid.org/0000-0002-0916-4015
Antonella Borrelli http://orcid.org/0000-0002-4439-6882
Franca Maria Tuccillo http://orcid.org/0000-0003-4167-2535
Lucrezia Silvestro http://orcid.org/0000-0002-4209-7694
Raffaele Palaia http://orcid.org/0000-0002-4299-3448
Franco Maria Buonaguro http://orcid.org/0000-0002-7491-7220
Funding Agency and Grant Number
Corresponding author Patrizia Bonelli, BSc, Research Scientist, Molecular Biology and Viral Oncology, Istituto Nazionale Tumori – IRCCS - Fondazione G Pascale, via Mariano Semmola, Napoli 80131, Italy. p.bonelli@istitutotumori.na.it
Keywords Gastric cancer; Molecular characterization; Biomarkers; Precision medicine; Targeted therapy;
Core Tip The onset of gastric cancer is linked to genetic alterations, and environmental and lifestyle factors. Recent classifications (the Cancer Genome Atlas, Asian Cancer Research Group) based on genetic alterations have shown significant neoplasia heterogeneity, which makes the practical application of such approaches more difficult. Numerous studies have been conducted on new specific targeted therapies in advanced gastric cancer in the field of precision medicine. The results have not been satisfactory in terms of survival, so elective therapy remains surgery associated with adjuvant and neoadjuvant chemotherapy. Future research should not underestimate the heterogeneity of gastric cancer when developing diagnostic and therapeutic strategies aimed toward improving patient survival.
Publish Date 2019-10-16 12:17
Citation Bonelli P, Borrelli A, Tuccillo FM, Silvestro L, Palaia R, Buonaguro FM. Precision medicine in gastric cancer. World J Gastrointest Oncol 2019; 11(10): 804-829
Url https://www.wjgnet.com/1948-5204/full/v11/i10/804.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i10.804
Full Article (PDF) WJGO-11-804.pdf
Full Article (Word) WJGO-11-804.docx
Manuscript File FP6993_ce16_CE1MS-edit2_Confirmed.doc
Answering Reviewers 48065-Answering reviewers.pdf
Audio Core Tip 48065-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 48065-Conflict-of-interest statement.pdf
Copyright License Agreement 48065-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 48065-Language certificate.pdf
Peer-review Report 48065-Peer-review(s).pdf
Scientific Misconduct Check 48065-Scientific misconduct check.pdf
Scientific Editor Work List 48065-Scientific editor work list.pdf