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Articles Published Processes
10/16/2019 12:17:24 PM | Browse: 882 | Download: 1181
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Received |
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2019-04-19 01:40 |
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Peer-Review Started |
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2019-04-22 00:12 |
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To Make the First Decision |
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2019-06-05 06:39 |
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Return for Revision |
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2019-06-06 03:03 |
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Revised |
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2019-07-11 13:55 |
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Second Decision |
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2019-09-04 08:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-09-05 03:19 |
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Articles in Press |
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2019-09-05 03:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-09-11 20:08 |
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Typeset the Manuscript |
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2019-10-14 09:34 |
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Publish the Manuscript Online |
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2019-10-16 12:17 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Precision medicine in gastric cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Patrizia Bonelli, Antonella Borrelli, Franca Maria Tuccillo, Lucrezia Silvestro, Raffaele Palaia and Franco Maria Buonaguro |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Patrizia Bonelli, BSc, Research Scientist, Molecular Biology and Viral Oncology, Istituto Nazionale Tumori – IRCCS - Fondazione G Pascale, via Mariano Semmola, Napoli 80131, Italy. p.bonelli@istitutotumori.na.it |
| Key Words |
Gastric cancer; Molecular characterization; Biomarkers; Precision medicine; Targeted therapy; |
| Core Tip |
The onset of gastric cancer is linked to genetic alterations, and environmental and lifestyle factors. Recent classifications (the Cancer Genome Atlas, Asian Cancer Research Group) based on genetic alterations have shown significant neoplasia heterogeneity, which makes the practical application of such approaches more difficult. Numerous studies have been conducted on new specific targeted therapies in advanced gastric cancer in the field of precision medicine. The results have not been satisfactory in terms of survival, so elective therapy remains surgery associated with adjuvant and neoadjuvant chemotherapy. Future research should not underestimate the heterogeneity of gastric cancer when developing diagnostic and therapeutic strategies aimed toward improving patient survival. |
| Publish Date |
2019-10-16 12:17 |
| Citation |
Bonelli P, Borrelli A, Tuccillo FM, Silvestro L, Palaia R, Buonaguro FM. Precision medicine in gastric cancer. World J Gastrointest Oncol 2019; 11(10): 804-829 |
| URL |
https://www.wjgnet.com/1948-5204/full/v11/i10/804.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v11.i10.804 |
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