BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/29/2019 10:56:48 AM | Browse: 431 | Download: 641
Publication Name World Journal of Clinical Cases
Manuscript ID 48144
Country China
Received
2019-04-13 05:32
Peer-Review Started
2019-04-15 00:53
To Make the First Decision
2019-08-02 03:06
Return for Revision
2019-08-02 06:38
Revised
2019-08-14 16:52
Second Decision
2019-08-23 10:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-26 23:32
Articles in Press
2019-08-26 23:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-09 18:25
Typeset the Manuscript
2019-09-25 10:20
Publish the Manuscript Online
2019-09-29 10:56
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an inhouse editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BYNC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Case Report
Article Title Underlying IgM heavy chain amyloidosis in treatment-refractory IgA nephropathy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Hai-Ting Wu, Yu-Bing Wen, Wei Ye, Bing-Yan Liu, Kai-Ni Shen, Rui-Tong Gao and Ming-Xi Li
ORCID
Author(s) ORCID Number
Hai-Ting Wu http://orcid.org/0000-0001-5725-021X
Yu-Bing Wen http://orcid.org/0000-0003-0438-8447
Wei Ye http://orcid.org/0000-0002-6116-6210
Bing-Yan Liu http://orcid.org/0000-0001-6359-5601
Kai-Ni Shen http://orcid.org/0000-0003-2381-339X
Rui-Tong Gao http://orcid.org/0000-0002-2117-5032
Ming-Xi Li http://orcid.org/0000-0002-1876-4186
Funding Agency and Grant Number
Corresponding Author Rui-Tong Gao, MD, Associate Professor, Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. gaoruitong@gmail.com
Key Words Monoclonal gammopathy of renal significance; IgA nephropathy; Renal biopsy; Laser microdissection/mass spectrometry; Case report;
Core Tip Monoclonal immunoglobulin can cause renal injury without hematological evidence of malignancy. These disorders can be missed, especially when combined with other kidney diseases. We present a patient diagnosed initially with IgA nephropathy and monoclonal gammopathy of undetermined significance (MGUS). Atypical characteristics and treatment refractoriness of IgA nephropathy led to the second renal biopsy. Amyloidosis was revealed and laser microdissection/mass spectrometry was used for typing. The patient improved well after therapy containing bortezomib. Renal involvement should be monitored closely in patients with MGUS, especially in those with pre-existing kidney diseases.
Publish Date 2019-09-29 10:56
Citation Wu HT, Wen YB, Ye W, Liu BY, Shen KN, Gao RT, Li MX. Underlying IgM heavy chain amyloidosis in treatment-refractory IgA nephropathy: A case report. World J Clin Cases 2019; 7(19):3055-3061
URL https://www.wjgnet.com/2307-8960/full/v7/i19/3055.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i19.3055
Full Article (PDF) WJCC-7-3055.pdf
Full Article (Word) WJCC-7-3055.docx
Manuscript File FP6979_ce25_CE1MS-edit2.docx
Answering Reviewers 48144-Answering reviewers.pdf
Audio Core Tip 48144-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 48144-Conflict-of-interest statement.pdf
Copyright License Agreement 48144-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 48144-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 48144-Language certificate.pdf
Peer-review Report 48144-Peer-review(s).pdf
Scientific Misconduct Check 48144-Scientific misconduct check.pdf
Scientific Editor Work List 48144-Scientific editor work list.pdf