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9/28/2019 10:12:50 AM | Browse: 561 | Download: 812
Publication Name World Journal of Gastroenterology
Manuscript ID 48244
Country China
Received
2019-04-26 01:26
Peer-Review Started
2019-04-26 03:00
To Make the First Decision
2019-05-27 00:34
Return for Revision
2019-05-31 02:26
Revised
2019-08-07 05:43
Second Decision
2019-08-16 09:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-19 13:40
Articles in Press
2019-08-19 13:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-09 22:52
Typeset the Manuscript
2019-09-27 08:57
Publish the Manuscript Online
2019-09-28 10:12
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title High mobility group box-1 release from H<Sub>2</Sub>O<Sub>2</Sub>-injured hepatocytes due to sirt1 functional inhibition
Manuscript Source Unsolicited Manuscript
All Author List Ting-Jie Ye, Yan-Lin Lu, Xiao-Feng Yan, Xu-Dong Hu and Xiao-Ling Wang
ORCID
Author(s) ORCID Number
Ting-Jie Ye http://orcid.org/0000-0003-2371-0374
Yan-Lin Lu http://orcid.org/0000-0002-3841-655X
Xiao-Feng Yan http://orcid.org/0000-0001-8510-0411
Xu-Dong Hu http://orcid.org/0000-0002-2166-0564
Xiao-Ling Wang http://orcid.org/0000-0002-0304-6464
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81503367; 81703832
Corresponding Author Xiao-Ling Wang, MD, Full Professor, Department of Biology, School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 210203, China. shengwuwang12@126.com
Key Words Sirtuin1; Poly ADP-ribose polymerase 1; High mobility group box-1; Hepatocytes; Hydrogen peroxide;
Core Tip High mobility group box 1 (HMGB1) is a protein in nucleus non-specifically binds to the minor grooves in DNA. Once released passively by necrotic and damaged cells, HMGB1 will become a damage-associated molecular pattern molecule triggering the inflammatory response and ultimately results in tissue damage. In the present study, we found that HMGB1 release from H2O2-injured hepatocytes due to sirt1 functional inhibition.
Publish Date 2019-09-28 10:12
Citation Ye TJ, Lu YL, Yan XF, Hu XD, Wang XL. High mobility group box-1 release from H2O2-injured hepatocytes due to sirt1 functional inhibition. World J Gastroenterol 2019; 25(36): 5434-5450
URL https://www.wjgnet.com/1007-9327/full/v25/i36/5434.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i36.5434
Full Article (PDF) WJG-25-5434.pdf
Manuscript File 48244-Review_Edited.doc
Answering Reviewers 48244-Answering reviewers.pdf
Audio Core Tip 48244-Audio core tip.mp3
Biostatistics Review Certificate 48244-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 48244-Conflict-of-interest statement.pdf
Copyright License Agreement 48244-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 48244-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 48244-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 48244-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 48244-Language certificate.pdf
Peer-review Report 48244-Peer-review(s).pdf
Scientific Misconduct Check 48244-Scientific misconduct check.pdf
Scientific Editor Work List 48244-Scientific editor work list.pdf