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Publication Name World Journal of Transplantation
Manuscript ID 4836
Country Canada
Received
2013-07-26 11:03
Peer-Review Started
2013-07-26 12:09
To Make the First Decision
2013-08-08 11:34
Return for Revision
2013-08-08 15:56
Revised
Second Decision
2013-08-29 07:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-08-29 10:03
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-10-11 00:00
Publish the Manuscript Online
2013-12-31 17:17
ISSN 2220-3230 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Editorial
Article Title Current status of clinical islet transplantation
Manuscript Source Invited Manuscript
All Author List Andrew R Pepper, Boris Gala-Lopez, Oliver Ziff and AM James Shapiro
Funding Agency and Grant Number
Corresponding Author AM James Shapiro, MD, PhD, Professor, Director of Clinical Islet and Living Donor Liver Transplant Programs, Department of Clinical Islet Transplant Program, University of Alberta, 2000 College Plaza, 8215-112th St, Edmonton T6G 2C8, Alberta, Canada. amjs@islet.ca
Key Words Islet transplantation; Type 1 diabetes; Immunosuppression
Core Tip Core tip: Since the initial inception of the “Edmonton protocol”, phenomenal progress has transpired in the last decade. These milestones were namely due to the implementation of numerous pre-clinical and clinical investigations, testing innovative agents allowing potent immunotolerance with minimal complications as well as alternative transplant sites to overcome limitations inherent to the current intraportal access. As a result nearly 80% of full or partial graft function, out of more than 300 transplants performed to date. As the field of continues to work and progress together, it is foreseeable that a cure for type 1 diabetes mellitus is obtainable in the near future.
Publish Date 2013-12-31 17:17
Citation Pepper AR, Gala-Lopez B, Ziff O, Shapiro AMJ. Current status of clinical islet transplantation. World J Transplant 2013; 3(4): 48-53
URL http://www.wjgnet.com/2220-3230/full/v3/i4/48.htm
DOI http://dx.doi.org/10.5500/wjt.v3.i4.48
Full Article (PDF) WJT-3-48.pdf
Full Article (Word) WJT-3-48.doc
Manuscript File 4836-Review.doc
Answering Reviewers 4836-Answering reviewers.pdf
Copyright License Agreement 4836-Copyright assignment.pdf
Peer-review Report 4836-Peer review(s).pdf
Scientific Editor Work List 4836-Scientific editor work list.doc