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9/15/2014 5:55:00 PM | Browse: 661 | Download: 518
Publication Name World Journal of Stem Cells
Manuscript ID 4840
Country/Territory United States
Received
2013-07-26 11:21
Peer-Review Started
2013-07-26 13:28
To Make the First Decision
2013-08-21 18:37
Return for Revision
2013-08-22 19:27
Revised
2013-09-06 07:22
Second Decision
2013-09-16 13:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-17 05:35
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-10-21 08:24
Publish the Manuscript Online
2013-10-31 14:50
ISSN 1948-0210 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biology
Manuscript Type Editorial
Article Title Advances in homology directed genetic engineering of human pluripotent and adult stem cells
Manuscript Source Invited Manuscript
All Author List Kalpith Ramamoorthi, Donald Curtis and Prashanth Asuri
Funding Agency and Grant Number
Corresponding Author Prashanth Asuri, PhD, Department of Bioengineering, Santa Clara University, 500 El Camino Real, Santa Clara, CA 95053, United States. asurip@scu.edu
Key Words Human stem cells; Genetic engineering; Engineered viruses; Synthetic restriction endonucleases
Core Tip This manuscript focuses on the development of novel technologies to precisely alter the human stem cell genome and highlights their implications for both basic and applied stem cell research. Specifically, we discuss the development of two main technologies: molecular engineering of viral vectors and design of artificial endonucleases. We also discuss the merits of combining these complementary approaches and suggest other possible strategies that could be explored to further improve genetic engineering of human stem cells.
Publish Date 2013-10-31 14:50
Citation Ramamoorthi K, Curtis D, Asuri P. Advances in homology directed genetic engineering of human pluripotent and adult stem cells. World J Stem Cells 2013; 5(4): 98-105
URL http://www.wjgnet.com/1948-0210/full/v5/i4/98.htm
DOI http://dx.doi.org/10.4252/wjsc.v5.i4.98
Full Article (PDF) WJSC-5-98.pdf
Manuscript File 4840-Review.doc
Answering Reviewers 4840-Answering reviewers.pdf
Copyright License Agreement 4840-Copyright Assignment.pdf
Peer-review Report 4840-Peer review(s).pdf
Scientific Editor Work List 4840-Scientific editor work list.doc