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Articles Published Processes
9/12/2019 8:50:34 AM | Browse: 786 | Download: 1916
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Received |
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2019-04-18 02:14 |
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Peer-Review Started |
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2019-04-18 07:09 |
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To Make the First Decision |
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2019-07-22 02:26 |
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Return for Revision |
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2019-07-23 02:22 |
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Revised |
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2019-07-30 13:45 |
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Second Decision |
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2019-08-16 09:15 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-08-19 13:43 |
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Articles in Press |
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2019-08-19 13:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-11 08:11 |
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Publish the Manuscript Online |
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2019-09-12 08:50 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Effect of Tong Xie Yao Fang on endogenous metabolites in urine of irritable bowel syndrome model rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xue-Ying Zhao, Jian-Wei Wang, Yue Yin, Kai Li, Miao Zhang and Fu-Ping Yan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jian-Wei Wang, PhD, Professor, School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin 150040, China. wangjianwei140918@126.com |
| Key Words |
Tong Xie Yao Fang; Irritable bowel syndrome; Liver-spleen disharmony; Endogenous metabolites; Metabolomics; |
| Core Tip |
Effects of Tong Xie Yao Fang on endogenous metabolites in urine of irritable bowel syndrome (IBS) model rats are investigated through Ultra-Performance Liquid Chromatography-quadrupole-time of flight-mass spectrometry. Tong Xie Yao Fang has the function of callback endogenous metabolite. Nine potential biomarkers were identified and 6 main metabolic pathways were analyzed. They were related to neurotransmitter metabolism, inflammatory immunity, emotional changes and energy metabolism in IBS disease, which may be the biological basis of IBS spleen deficiency and liver hyperactivity syndrome. |
| Publish Date |
2019-09-12 08:50 |
| Citation |
Zhao YX, Wang JW, Yin Y, Li K, Zhang M, Yan FP. Effect of Tong Xie Yao Fang on endogenous metabolites in urine of irritable bowel syndrome model rats. World J Gastroenterol 2019; 25(34): 5134-5151 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i34/5134.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i34.5134 |
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