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Articles Published Processes
10/17/2019 6:26:08 AM | Browse: 627 | Download: 696
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Received |
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2019-04-28 01:11 |
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Peer-Review Started |
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2019-05-09 02:31 |
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To Make the First Decision |
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2019-08-06 01:13 |
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Return for Revision |
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2019-08-06 05:53 |
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Revised |
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2019-08-13 21:17 |
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Second Decision |
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2019-08-30 08:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-09-05 17:58 |
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Articles in Press |
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2019-09-05 17:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-11 09:07 |
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Publish the Manuscript Online |
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2019-10-17 06:26 |
| ISSN |
2220-3141(online) |
| Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Review |
| Article Title |
Anticoagulation with direct thrombin inhibitors during extracorporeal membrane oxygenation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Barry Burstein, Patrick M Wieruszewski, Yan-Jun Zhao and Nathan Smischney |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nathan Smischney, MD, MSc, Assistant Professor, Department of Anesthesia, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States. smischney.nathan@mayo.edu |
| Key Words |
Extracorporeal membrane oxygenation; Anticoagulants; Antithrombins; Bivalirudin; Argatroban; Heparin |
| Core Tip |
In contrast to unfractionated heparin, direct thrombin inhibitors are not associated with heparin-induced thrombocytopenia or acquired antithrombin deficiency. Direct thrombin inhibitors, specifically bivalirudin and argatroban, are equally safe and possibly more efficacious than unfractionated heparin. Dosage and monitoring parameters are easily manageable and more predictable than unfractionated heparin. As extracorporeal membrane oxygenation increases in use, direct thrombin inhibitors may potentially be considered as a primary anticoagulant in patients with or without complications of unfractionated heparin. |
| Publish Date |
2019-10-17 06:26 |
| Citation |
Burstein B, Wieruszewski PM, Zhao YJ, Smischney N. Anticoagulation with direct thrombin inhibitors during extracorporeal membrane oxygenation. World J Crit Care Med 2019; 8(6): 87-98 |
| URL |
https://www.wjgnet.com/2220-3141/full/v8/i6/87.htm |
| DOI |
https://dx.doi.org/10.5492/wjccm.v8.i6.87 |
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