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9/7/2019 4:43:36 AM | Browse: 800 | Download: 1043
Publication Name World Journal of Gastroenterology
Manuscript ID 48774
Country Ireland
Received
2019-05-09 02:27
Peer-Review Started
2019-05-10 03:17
To Make the First Decision
2019-07-22 02:18
Return for Revision
2019-07-22 06:26
Revised
2019-07-28 21:52
Second Decision
2019-08-02 10:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-07 09:37
Articles in Press
2019-08-07 09:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-09-04 03:23
Publish the Manuscript Online
2019-09-07 04:43
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Neoadjuvant radiotherapy for rectal cancer management
Manuscript Source Invited Manuscript
All Author List Gerard Feeney, Rishabh Sehgal, Margaret Sheehan, Aisling Hogan, Mark Regan, Myles Joyce and Michael Kerin
ORCID
Author(s) ORCID Number
Gerard Feeney http://orcid.org/0000-0002-1527-793X
Rishabh Sehgal http://orcid.org/0000-0002-1905-3378
Margaret Sheehan http://orcid.org/0000-0001-5475-392X
Aisling Hogan http://orcid.org/0000-0002-8166-732X
Mark Regan http://orcid.org/0000-0003-1348-7877
Myles Joyce http://orcid.org/0000-0002-9102-8636
Michael Kerin http://orcid.org/0000-0003-4164-5561
Funding Agency and Grant Number
Funding Agency Grant Number
NBCRI, Symptomatic Breast Unit, University Hospital Galway
Corresponding Author Gerard Feeney, MBChB, Doctor, Department of General/Colorectal Surgery, Lambe Institute, Galway University Hospital, Newcastle Road, Galway H91 YR71, Ireland. g.feeney3@nuigalway.ie
Key Words Rectal cancer; Neoadjuvant therapy; Low anterior resection syndrome; Stoma; Transanal endoscopic microsurgery; Trans-anal total mesorectal excision
Core Tip Neoadjuvant radiotherapy aims to downstage tumours for a more effective oncological resection. Studies have shown that both long and short course pre-operative radiotherapy confers benefits to local recurrence. Some patients completely respond to radiotherapy and have been enrolled in surveillance programmes without undergoing surgery. It is essential to be aware of the disadvantages associated with radiotherapy. Radiation therapy increases the risk of anorectal and genitourinary dysfunction which have a deleterious impact on quality of life. Thus it is imperative to accurately identify patients who are likely to benefit from neoadjuvant radiotherapy in order to minimise morbidity and improve patient outcomes.
Publish Date 2019-09-07 04:43
Citation Feeney G, Sehgal R, Sheehan M, Hogan A, Regan M, Joyce M, Kerin M. Neoadjuvant radiotherapy for rectal cancer management. World J Gastroenterol 2019;25(33): 4850-4869
URL https://www.wjgnet.com/1007-9327/full/v25/i33/4850.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i33.4850
Full Article (PDF) WJG-25-4850.pdf
Full Article (Word) WJG-25-4850.docx
Manuscript File 48774-Review.docx
Answering Reviewers 48774-Answering reviewers.pdf
Audio Core Tip 48774-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 48774-Conflict-of-interest statement.pdf
Copyright License Agreement 48774-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 48774-Grant application form(s).pdf
Peer-review Report 48774-Peer-review(s).pdf
Scientific Misconduct Check 48774-Google-MA RY-2.png
Scientific Misconduct Check 48774-Scientific misconduct check.pdf
Scientific Editor Work List 48774-Scientific editor work list.pdf