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Articles Published Processes
9/12/2014 8:41:00 PM | Browse: 692 | Download: 833
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Received |
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2013-07-31 10:18 |
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Peer-Review Started |
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2013-07-31 16:41 |
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To Make the First Decision |
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2013-08-21 18:52 |
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Return for Revision |
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2013-08-27 10:07 |
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Revised |
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2013-09-05 12:16 |
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Second Decision |
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2013-09-16 17:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2013-09-17 06:37 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-10-25 20:49 |
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Publish the Manuscript Online |
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2013-11-16 18:29 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Potential role of Helicobacter pylori infection in nonalcoholic fatty liver disease
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Manuscript Source |
Invited Manuscript |
All Author List |
Meng Li, Zhe Shen and You-Ming Li |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81230012 |
Zhejiang Provincial Laboratory Animal Science Technology Program of China |
2011C37088 |
National Natural Science Foundation of China |
81300303 |
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Corresponding Author |
You-Ming Li, Professor, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zliyouming@126.com |
Key Words |
Helicobacter pylori; Nonalcoholic fatty liver disease; Insulin resistance; Inflammation; Cytokines |
Core Tip |
A growing body of evidence suggests that Helicobacter pylori (H. pylori) infection is linked with nonalcoholic fatty liver disease (NAFLD). There are some potential pathogenic mediators and mechanisms involved in this progress, including fetuin-A, tumor necrosis factor-? and adiponectin. Long-term H. pylori infection may cause insulin resistance and inflammation, contributing to NAFLD. H. pylori toxins in the portal circulation arising from the gastroduodenal area may be another intriguing point, which might be related to the increased intestinal permeability in patients with NAFLD. It is hoped that eradication of H. pylori will provide a new treatment strategy for NAFLD.
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Publish Date |
2013-11-16 18:29 |
Citation |
Li M, Shen Z, Li YM. Potential role of Helicobacter pylori infection in nonalcoholic fatty liver disease. World J Gastroenterol 2013; 19(41): 7024-7031 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i41/7024.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i41.7024 |
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