Publication Name	World Journal of Hepatology
Manuscript ID	4909
Country	Germany

Received	2013-08-01 09:40
Peer-Review Started	2013-08-02 01:42
To Make the First Decision	2013-09-02 15:59
Return for Revision	2013-09-05 11:58
Revised	2013-09-17 16:46
Second Decision	2013-12-10 16:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-12-11 10:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-12-17 20:18
Typeset the Manuscript	2014-01-17 18:23
Publish the Manuscript Online	2014-01-26 15:15

ISSN	1948-5182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Drug and herb induced liver injury: Council for International Organizations of Medical Sciences scale for causality assessment
Manuscript Source	Invited Manuscript
All Author List	Rolf Teschke, Albrecht Wolff, Christian Frenzel, Alexander Schwarzenboeck, Johannes Schulze and Axel Eickhoff
Funding Agency and Grant Number
Corresponding Author	Rolf Teschke, MD, Professor of Medicine, Department of Internal Medicine Ⅱ, Klinikum Hanau, Academic Teaching Hospital of the Medical Faculty of the Goethe University of Frankfurt/Main, Leimenstrasse 20, D-63450 Hanau, Germany. rolf.teschke@gmx.de
Key Words	Drug induced liver injury; Drug hepatotoxicity; Herb induced liver injury; Herbal hepatotoxicity; Causality assessment
Core Tip	We propose that the attending physicians caring for patients with assumed drug induced liver injury and herb induced liver injury should use the Council for International Organizations of Medical Sciences (CIOMS) scale for causality assessment. This approach includes the option of subsequent refinement of the CIOMS based results by expert panels and regulatory agencies. The use of the CIOMS scale as an identical tool for all involved parties will allow early and prospective collection of all relevant data required for a valid causality assessment in clinical hepatology.
Publish Date	2014-01-26 15:15
Citation	Teschke R, Wolff A, Frenzel C, Schwarzenboeck A, Schulze J, Eickhoff A. Drug and herb induced liver injury: Council for International Organizations of Medical Sciences scale for causality assessment. World J Hepatol 2014; 6(1): 17-32
URL	http://www.wjgnet.com/1948-5182/full/v6/i1/17.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i1.17

Full Article (PDF)	WJH-6-1.pdf
Full Article (Word)	WJH-6-1.doc
Manuscript File	4909-Review.doc
Answering Reviewers	4909-Answering reviewers.pdf
Copyright License Agreement	4909-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20130731152616.jpg
Peer-review Report	4909-Peer reviewer(s).pdf
Scientific Editor Work List	4909-Scientific editor work list.doc