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Articles Published Processes
8/26/2019 8:35:39 AM | Browse: 671 | Download: 702
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Received |
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2019-05-29 08:26 |
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Peer-Review Started |
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2019-06-04 06:24 |
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To Make the First Decision |
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2019-08-02 06:39 |
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Return for Revision |
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2019-08-05 02:32 |
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Revised |
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2019-08-10 19:54 |
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Second Decision |
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2019-08-13 06:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-08-13 08:26 |
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Articles in Press |
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2019-08-13 08:26 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-08-23 01:40 |
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Publish the Manuscript Online |
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2019-08-26 08:35 |
| ISSN |
1948-9366 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Systematic review of anorectal leiomyosarcoma: Current challenges and recent advances
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mohammed O Nassif, Razan Habib, Luai Almarzouki and Nora Trabulsi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed O Nassif, FACS, FRSC, MD, Doctor, Department of General Surgery, King Abdulaziz University, PO Box 80215, Aljamaa St, Jeddah 21589, Saudi Arabia. dr.monassif@gmail.com |
| Key Words |
Leiomyosarcoma; Rectal neoplasms; Anal neoplasms; Gastrointestinal neoplasms; Soft tissue neoplasms; |
| Core Tip |
The current mainstay treatment of anorectal leiomyosarcoma is surgical resection with negative margins. Based on the published case series and reports, sphincter-preserving surgery followed by radiotherapy yields local recurrence rates that are comparable to radical resection. Moreover, neoadjuvant radiation improves local recurrence rates, as compared to adjuvant radiation. Adjuvant chemotherapy significantly improves rates of distant recurrence and overall survival; however, the choice to use chemotherapy in this setting should be determined according to a multidisciplinary team consideration of patient-related factors and treatment toxicity. Since local and distant tumor recurrences are common, even years after resection, post-surgery long-term follow-up is needed. |
| Publish Date |
2019-08-26 08:35 |
| Citation |
Nassif MO, Habib RA, Almarzouki LZ, Trabulsi NH. Systematic review of anorectal leiomyosarcoma: Current challenges and recent advances. World J Gastrointest Surg 2019; 11(8): 334-341 |
| URL |
https://www.wjgnet.com/1948-9366/full/v11/i8/334.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v11.i8.334 |
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