| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Observational Study |
| Article Title |
Evaluation and comparison of short chain fatty acids composition in gut diseases
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Elena Niccolai, Simone Baldi, Federica Ricci, Edda Russo, Giulia Nannini, Marta Menicatti, Giovanni Poli, Antonio Taddei, Gianluca Bartolucci, Antonino Salvatore Calabrò, Francesco Claudio Stingo and Amedeo Amedei |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Italian Society for Celiac Disease and Foundation for Celicac Disease |
007_FC_2016 |
| Regione Toscana (The Programma Attuativo Regionale Toscana funded by FAS) |
MICpROBIMM |
|
| Corresponding Author |
Amedeo Amedei, BSc, Associate Professor, Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 03, Firenze 50134, Florence, Italy. aamedei@unifi.it |
| Key Words |
Short chain fatty acids; Microbiota; Colorectal cancer; Adenoma; Celiac disease; |
| Core Tip |
An altered gut microbiota is usually responsible for a reduction of short chain fatty acids (SCFAs) concentration. In this study, we analyse through gas-chromatography coupled with mass spectrometry the fecal SCFAs’ concentration in patients with various gut diseases [celiac disease (CD), adenomatous polyposis (AP) and colorectal cancer (CRC)]. Altought the small sample size of study does not allow us to reach definitive conclusions, our findings suggest the existence of a fecal SCFAs fingerprint in patients with CRC amd AP distinguishable from healthy controls. On the contrary, no differences between celiac patients and healthy controls was observed. |
| Publish Date |
2019-09-28 10:12 |
| Citation |
Niccolai E, Baldi S, Ricci F, Russo E, Nannini G, Marta Menicatti M, Poli G, Taddei A, Bartolucci G, Calabrò AS, Stingo FC, Amedei A. Comparative analysis of fecal short chain fatty acids profiles in gut diseases. World J Gastroenterol 2019; 25(36): 5543-5558 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i36/5543.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i36.5543 |
