Publication Name	World Journal of Cardiology
Manuscript ID	50324
Country	United States

Received	2019-07-12 20:42
Peer-Review Started	2019-07-17 10:37
To Make the First Decision	2019-08-06 07:00
Return for Revision	2019-08-20 01:55
Revised	2019-10-17 17:29
Second Decision	2019-11-26 08:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-26 22:24
Articles in Press	2019-11-26 22:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-23 03:53
Publish the Manuscript Online	2019-12-25 12:06

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Diagnosis and treatment of heart failure with preserved left ventricular ejection fraction
Manuscript Source	Unsolicited Manuscript
All Author List	Robert J Henning
ORCID	Author(s) ORCID Number Robert J Henning http://orcid.org/0000-0002-6958-4847
Funding Agency and Grant Number
Corresponding Author	Robert J Henning, MD, Doctor, Emeritus Professor, College of Public Health, University of South Florida, 13201 Bruce B Downs Blvd, Tampa, FL 33612, United States. roberthenningmd@gmail.com
Key Words	Diastolic heart failure; Myocardial stiffness; Incomplete left ventricular relaxation; Echocardiographic heart failure criteria; Pulmonary artery pressure monitoring; Drug treatment
Core Tip	Three million people in United States have heart failure with normal left ventricular systolic function but abnormal diastolic function due to increased myocardial stiffness. These patients are often elderly women with hypertension, ischemic heart disease, atrial fibrillation, obesity, diabetes mellitus, renal disease, or obstructive lung disease. The annual mortality rate of these patients is 8%-12% per year. The diagnosis is based on history, physical examination, laboratory data, echocardiography, and, when necessary, by cardiac catheterization. These patients often require weight reduction, an exercise program, aggressive control of blood pressure and heart rate, and diuretics. If significant coronary heart disease is present, coronary revascularization should be considered.
Publish Date	2019-12-25 12:06
Citation	Henning RJ. Diagnosis and treatment of heart failure with preserved left ventricular ejection fraction. World J Cardiol 2020; 12(1): 7-25
URL	https://www.wjgnet.com/1949-8462/full/v12/i1/7.htm
DOI	https://dx.doi.org/10.4330/wjc.v12.i1.7

Full Article (PDF)	WJC-12-7.pdf
Full Article (Word)	WJC-12-7.docx
Manuscript File	50324-Review.docx
Answering Reviewers	50324-Answering reviewers.pdf
Audio Core Tip	50324-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	50324-Conflict-of-interest statement.pdf
Copyright License Agreement	50324-Copyright license agreement.pdf
Peer-review Report	50324-Peer-review(s).pdf
Scientific Misconduct Check	50324-Scientific misconduct check.pdf
Scientific Editor Work List	50324-Scientific editor work list.pdf