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9/28/2019 10:12:50 AM | Browse: 800 | Download: 1342
Publication Name World Journal of Gastroenterology
Manuscript ID 50539
Country China
Received
2019-07-25 12:58
Peer-Review Started
2019-07-25 12:59
To Make the First Decision
2019-08-19 00:45
Return for Revision
2019-08-20 06:57
Revised
2019-08-25 13:37
Second Decision
2019-08-30 11:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-09 05:57
Articles in Press
2019-09-09 05:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-16 02:35
Typeset the Manuscript
2019-09-27 07:35
Publish the Manuscript Online
2019-09-28 10:12
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Diagnostic value of the gamma-glutamyltransferase/aspartate aminotransferase ratio, protein induced by vitamin K absence or antagonist II and alpha-fetoprotein in hepatitis B virus-related hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Qiang Wang, Qi Chen, Xia Zhang, Xiao-Lan Lu, Qin Du, Tao Zhu, Quo-Yuan Zhang, Dong-Sheng Wang and Qu-Ming Fan
ORCID
Author(s) ORCID Number
Qiang Wang http://orcid.org/0000-0001-9283-7729
Qi Chen http://orcid.org/0000-0003-4991-8499
Xia Zhang http://orcid.org/0000-0002-9594-9985
Xiao-Lan Lu http://orcid.org/0000-0001-6273-4403
Qin Du http://orcid.org/0000-0002-2933-0228
Tao Zhu http://orcid.org/0000-0003-3344-8592
Quo-Yuan Zhang http://orcid.org/0000-0003-1368-7633
Dong-Sheng Wang http://orcid.org/0000-0003-1192-8798
Qu-Ming Fan http://orcid.org/0000-0001-8469-9717
Funding Agency and Grant Number
Corresponding Author Qu-Ming Fan, PhD, Research Assistant Professor, Department of Laboratory Medicine, Affiliated Hospital of North Sichuan Medical College, 63# wenhua road, nanchong 637000, China. fanqum@163.com
Key Words Gamma-glutamyltransferase; Aspartate aminotransferase; Protein induced by vitamin K absence or antagonist II; Alpha-fetoprotein; Hepatitis B virus; Hepatocellular carcinoma
Core Tip This study shown that the ratio gamma-glutamyltransferase and aspartate aminotransferase (γ-GT/AST ratio) was not correlated with the tumour size in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), and there was no difference in the AUROC between early-stage HBV-related HCC and HBV-related HCC, indicated that the γ-GT/AST ratio may be more useful than protein induced by vitamin K absence or antagonist II (PIVKA-II) and alpha-fetoprotein (AFP) in the diagnosis of earlier-stage HBV-related HCC. PIVKA-II and AFP combined with the γ-GT/AST ratio can enhance the diagnostic value of these biomarkers in different categories of HBV-related HCC.
Publish Date 2019-09-28 10:12
Citation Wang Q, Chen Q, Zhang X, Lu XL, Du Q, Zhu T, Zhang GY, Wang DS, Fan QM. Diagnostic value of the gamma-glutamyltransferase/aspartate aminotransferase ratio, protein induced by vitamin K absence or antagonist II and alpha-fetoprotein in hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol 2019; 25(36): 5515-5529
URL https://www.wjgnet.com/1007-9327/full/v25/i36/5515.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i36.5515
Full Article (PDF) WJG-25-5515.pdf
Full Article (Word) WJG-25-5515.docx
Manuscript File 50539-Review_Edited.doc
Answering Reviewers 50539-Answering reviewers.pdf
Audio Core Tip 50539-Audio core tip.mp3
Biostatistics Review Certificate 50539-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 50539-Conflict-of-interest statement.pdf
Copyright License Agreement 50539-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 50539-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 50539-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 50539-Language certificate.pdf
Peer-review Report 50539-Peer-review(s).pdf
Scientific Misconduct Check 50539-Bing-Tang JZ.png
Scientific Misconduct Check 50539-Scientific misconduct check.pdf
Scientific Editor Work List 50539-Scientific editor work list.pdf