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Publication Name World Journal of Dermatology
Manuscript ID 5063
Country
Received
2013-08-13 08:22
Peer-Review Started
2013-08-13 14:08
To Make the First Decision
2013-08-21 18:39
Return for Revision
2013-08-22 19:19
Revised
Second Decision
2013-09-16 14:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-17 05:38
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-09-29 14:13
Publish the Manuscript Online
2013-10-31 15:06
ISSN 2218-6190 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Dermatology
Manuscript Type Editorial
Article Title Molecular mimicry in cutaneous autoimmune diseases
Manuscript Source
All Author List Fabrizio Guarneri and Claudio Guarneri
Funding Agency and Grant Number
Corresponding Author Fabrizio Guarneri, MD, Professor, Department of Clinical and Experimental Medicine, University of Messina, AOU Policlinico “G. Martino”, Via Consolare Valeria 1, 98125 Messina, Italy. f.guarneri@tiscali.it
Key Words Molecular mimicry; Dermatology; Autoimmunity; Bioinformatics; Amino acid sequence homology
Core Tip Molecular mimicry between microbial and human proteins is often used by pathogens to control biosynthetic/regulatory pathways of infected cells and elude immune reaction of host. In predisposed subjects, immune response against non-self molecules can, because of molecular mimicry, turn against self antigens and trigger autoimmune diseases. This mechanism, which explains the specific epidemiological link between some infections and some autoimmune diseases, is known and experimentally confirmed in several disciplines, but much less studied in dermatology. Bioinformatics can greatly help and boost research by quickly and almost inexpensively identifying molecules most probably involved in triggering autoimmunity via molecular mimicry.
Publish Date 2013-10-31 15:06
Citation Guarneri F, Guarneri C. Molecular mimicry in cutaneous autoimmune diseases. World J Dermatol 2013; 2(4): 36-43
URL http://www.wjgnet.com/2218-6190/full/v2/i4/36.htm
DOI http://dx.doi.org/10.5314/wjd.v2.i4.36
Full Article (PDF) WJD-2-36.pdf
Manuscript File 5063-Review.doc
Answering Reviewers 5063-Answering reviewers.pdf
Biostatistics Review Certificate Biostatistician_Review_Report_20130812175809.doc
Copyright License Agreement 5063-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Ethics_Committee_20130812175628.doc
Peer-review Report 5063-Peer review(s).pdf
Scientific Editor Work List 5063-Scientific editor work list.doc