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12/28/2019 9:29:28 AM | Browse: 659 | Download: 1125
Publication Name World Journal of Gastroenterology
Manuscript ID 51543
Country/Territory China
Received
2019-09-29 02:44
Peer-Review Started
2019-09-21 07:11
To Make the First Decision
Return for Revision
2019-11-27 04:55
Revised
2019-12-03 11:02
Second Decision
2019-12-13 07:53
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-14 02:42
Articles in Press
2019-12-14 02:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-12-20 00:39
Typeset the Manuscript
2019-12-27 07:13
Publish the Manuscript Online
2019-12-28 09:29
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Comprehensive multi-omics analysis identified core molecular processes in esophageal cancer and revealed GNGT2 is a potential prognostic marker
Manuscript Source Unsolicited Manuscript
All Author List Guo-Min Liu, Tian-Cheng Lu, Li-Wei Duan, Wen-Yuan Jia, Yun Liu, Xuan Ji, Mao-Lei Sun and Yun-Gang Luo
ORCID
Author(s) ORCID Number
Guo-Min Liu http://orcid.org/0000-0002-6567-5768
Tian-Cheng Lu http://orcid.org/0000-0003-4174-3030
Li-Wei Duan http://orcid.org/0000-0001-7995-4322
Wen-Yuan Jia http://orcid.org/0000-0003-2879-4749
Yun Liu http://orcid.org/0000-0003-0731-024X
Xuan Ji http://orcid.org/0000-0002-3810-0395
Mao-Lei Sun http://orcid.org/0000-0002-7601-771X
Yun-Gang Luo http://orcid.org/0000-0002-6646-2430
Funding Agency and Grant Number
Corresponding Author Yun-Gang Luo, MD, Attending Doctor, Jilin Provincial Medicine Anti-Tumor Engineering Center, The Second Hospital of Jilin University, No. 218, Ziqiang Street, Changchun 130041, Jilin Province, China. luode544101@163.com
Key Words Esophageal cancer; Molecular pathogenesis; Enrichment analysis; Gene interaction module; Regulatory factors; GNGT2
Core Tip Based on the esophageal cancer-associated RNA-seq in The Cancer Genome Atlas, this study studied the differentially expressed genes of esophageal cancer at various stages, constructed a protein-protein interaction network, obtained 14 dysfunctional modules, and screened out Hub genes. We further performed enrichment analysis to predict non-coding RNA and transcription factors, as well as methylation analysis of the genes in the module. A series of regulatory factors we predicted have a certain degree of regulation on the potential dysfunction mechanism of esophageal cancer, which provides a new idea for the subsequent study of esophageal cancer.
Publish Date 2019-12-28 09:29
Citation Liu GM, Lu TC, Duan LW, Jia WY, Liu Y, Ji X, Sun ML, Luo YG. Comprehensive multi-omics analysis identified core molecular processes in esophageal cancer and revealed GNGT2 is a potential prognostic marker. World J Gastroenterol 2019; 25(48): 6890-6901
URL https://www.wjgnet.com/1007-9327/full/v25/i48/6890.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i48.6890
Full Article (PDF) WJG-25-6890.pdf
Full Article (Word) WJG-25-6890.docx
Manuscript File 51543-Review-Filipodia.docx
Answering Reviewers 51543-Answering reviewers.pdf
Audio Core Tip 51543-Audio core tip.mp3
Biostatistics Review Certificate 51543-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 51543-Conflict-of-interest statement.pdf
Copyright License Agreement 51543-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 51543-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 51543-Language certificate.pdf
Peer-review Report 51543-Peer-review(s).pdf
Scientific Misconduct Check 51543-Scientific misconduct check.pdf
Scientific Editor Work List 51543-Scientific editor work list.pdf