Publication Name	World Journal of Gastroenterology
Manuscript ID	51569
Country	China

Received	2019-09-23 02:43
Peer-Review Started	2019-09-23 02:44
To Make the First Decision	2019-11-04 08:14
Return for Revision	2019-11-07 11:09
Revised	2019-11-15 02:17
Second Decision	2019-11-28 09:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-29 04:10
Articles in Press	2019-11-29 04:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-12-05 04:44
Typeset the Manuscript	2019-12-19 07:09
Publish the Manuscript Online	2019-12-20 10:20

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	MiR-96-5p silence induces cell apoptosis in gastric adenocarcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	He-Ying Zhou, Chun-Qi Wu and En-Xu Bi
ORCID	Author(s) ORCID Number He-Ying Zhou http://orcid.org/0000-0001-6216-392X Chun-Qi Wu http://orcid.org/0000-0002-8621-8937 En-Xu Bi http://orcid.org/0000-0003-0043-782X
Funding Agency and Grant Number
Corresponding Author	En-Xu Bi, BSc, Chief Physician, General Surgery, Qingdao West Coast New Area Central Hospital, No. 9 Huangpujiang Road, Qingdao Development Zone, Qingdao 266555, Shandong Province, China. biepinqiang71@163.com
Key Words	Gastric adenocarcinoma; Differently expressed miRNAs; Prognosis; MicroRNA-96-5p; Cell apoptosis; The Cancer Genome Atlas
Core Tip	Gastric adenocarcinoma (GAC) is the most common malignant tumor. It is important to further reveal novel diagnostic and therapeutic methods, as well as underlying the molecular mechanism of GAC. This study aimed to search for novel miRNAs related to GAC prognosis. Finding from this work identified six miRNAs related to prognosis, including miR-96-5p, miR-125-5p, miR-145-3p, miR-222-5p, miR-379-3p, and miR-652-5p, in GAC samples. Furthermore, downregulated miR-96-5p markedly induced cell apoptosis through targeting ZDHHC5. Current findings provide a potential molecular mechanism of miR-96-5p in GAC.
Publish Date	2019-12-20 10:20
Citation	Zhou HY, Wu CQ, Bi EX. MiR-96-5p silence induces cell apoptosis in gastric adenocarcinoma. World J Gastroenterol 2019; 25(47): 6823-6834
URL	https://www.wjgnet.com/1007-9327/full/v25/i47/6823.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i47.6823

Full Article (PDF)	WJG-25-6823.pdf
Full Article (Word)	WJG-25-6823.docx
Manuscript File	51569-Review-Filipodia.docx
Answering Reviewers	51569-Answering reviewers.pdf
Audio Core Tip	51569-Audio core tip.mp3
Biostatistics Review Certificate	51569-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	51569-Conflict-of-interest statement.pdf
Copyright License Agreement	51569-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	51569-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	51569-Language certificate.pdf
Peer-review Report	51569-Peer-review(s).pdf
Scientific Misconduct Check	51569-Scientific misconduct check.pdf
Scientific Editor Work List	51569-Scientific editor work list.pdf