| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Usefulness of autotaxin for the complications of liver cirrhosis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xue Shao, Uojima Haruki, Toru Setsu, Tomomi Okubo, Masanori Atsukawa, Yoshihiro Furuichi, Yoshitaka Arase, Hisashi Hidaka, Yoshiaki Tanaka, Takahide Nakazawa, Makoto Kako, Tatehiro Kagawa, Katsuhiko Iwakiri, Shuji Terai and Wasaburo Koizumi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Uojima Haruki, MD, Doctor, Department of Gastroenterology, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa 247-8533, Japan. kiruha555@yahoo.co.jp |
| Key Words |
Autotaxin; Hepatic encephalopathy; Hepatic ascites; Liver fibrosis; Biomarker; |
| Core Tip |
Autotaxin (ATX) has been reported as a novel biomarker for estimating liver fibrosis stages, and researchers have reported that this fibrosis marker correlated closely with more advanced fibrosis. Especially, the assessment for the complications of liver cirrhosis (LC) is valuable in helping to make treatment decisions. However, data on the clinical usefulness of novel fibrosis markers in assessing the complications of LC are scant. This study showed that ATX is a useful biomarker for assessing the complications of LC. Especially, the use of ATX in men was more effective than any other biomarker for detecting hepatic encephalopathy and varix ruptures. |
| Publish Date |
2020-01-07 07:47 |
| Citation |
Shao X, Uojima H, Setsu T, Okubo T, Atsukawa M, Furuichi Y, Arase Y, Hidaka H, Tanaka Y, Nakazawa T, Kako M, Kagawa T, Iwakiri K, Terai S, Koizumi W. Usefulness of autotaxin for the complications of liver cirrhosis. World J Gastroenterol 2020; 26(1): 97-108 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i1/97.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i1.97 |
