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3/14/2020 3:03:29 PM | Browse: 682 | Download: 1384
Publication Name World Journal of Gastroenterology
Manuscript ID 52691
Country/Territory China
Received
2019-11-14 03:03
Peer-Review Started
2019-11-14 03:03
To Make the First Decision
Return for Revision
2019-12-30 22:17
Revised
2020-01-06 07:58
Second Decision
2020-01-18 10:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-01-18 18:47
Articles in Press
2020-01-18 18:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-02-19 23:18
Typeset the Manuscript
2020-03-13 09:02
Publish the Manuscript Online
2020-03-14 15:03
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Technetium-99m-labeled macroaggregated albumin lung perfusion scan for diagnosis of hepatopulmonary syndrome: A prospective study comparing brain uptake and whole-body uptake
Manuscript Source Unsolicited Manuscript
All Author List He Zhao, Jiaywei Tsauo, Xiao-Wu Zhang, Huai-Yuan Ma, Ning-Na Weng, Gong-Shun Tang and Xiao Li
ORCID
Author(s) ORCID Number
He Zhao http://orcid.org/0000-0002-3262-9116
Jiaywei Tsauo http://orcid.org/0000-0002-5655-7989
Xiao-Wu Zhang http://orcid.org/0000-0003-1961-0151
Huai-Yuan Ma http://orcid.org/0000-0002-4666-000X
Ning-Na Weng http://orcid.org/0000-0002-3513-1372
Gong-Shun Tang http://orcid.org/0000-0002-6731-486X
Xiao Li http://orcid.org/0000-0001-9420-9558
Funding Agency and Grant Number
Funding Agency Grant Number
National Key R and D Program of China 2017YFC0107800
CAMS Initiative for Innovative Medicine 2016-12M-2-004
Corresponding Author Xiao Li, MD, PhD, Doctor, Postdoc, Professor, Department of Interventional Therapy, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. simonlixiao@gmail.com
Key Words Portal Hypertension; Intrapulmonary Vascular Dilations; Radionuclide Imaging; Technetium-99m-labeled Macroaggregated albumin Lung Perfusion Scan; Diagnostic Tests; Sensitivity and Specificity
Core Tip Hepatopulmonary syndrome is a common complication of liver disease which impairs the lungs’ ability to oxygenate blood, leading to debilitating symptoms, such as shortness of breath. Intrapulmonary vascular dilations, a hallmark of hepatopulmonary syndrome, can be detected using technetium-99m-labeled macroaggregated albumin lung perfusion scan, however, of the two most commonly used methods of result interpretation (i.e., brain uptake and whole-body uptake), it is unclear which is more accurate. In this study of 69 patients with liver cirrhosis, we found that whole-body uptake is more accurate than brain uptake for detecting intrapulmonary vascular dilations.
Publish Date 2020-03-14 15:03
Citation Zhao H, Tsauo J, Zhang X, Ma H, Weng N, Tang G, Li X. Technetium-99m-labeled macroaggregated albumin lung perfusion scan for diagnosis of hepatopulmonary syndrome: A prospective study comparing brain uptake and whole-body uptake. World J Gastroenterol 2020; 26(10): 1088-1097
URL https://www.wjgnet.com/1007-9327/full/v26/i10/1088.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i10.1088
Full Article (PDF) WJG-26-1088.pdf
Full Article (Word) WJG-26-1088.docx
Manuscript File 52691-Review-Filipodia3.docx
Answering Reviewers 52691-Answering reviewers.pdf
Audio Core Tip 52691-Audio core tip.m4a
Biostatistics Review Certificate 52691-Biostatistics statement.pdf
Clinical Trial Registration Statement 52691-Clinical Trial Registration Statement.pdf
Conflict-of-Interest Disclosure Form 52691-Conflict-of-interest statement.pdf
Copyright License Agreement 52691-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52691-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 52691-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 52691-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 52691-Language certificate.pdf
Peer-review Report 52691-Peer-review(s).pdf
Scientific Misconduct Check 52691-Scientific misconduct check.pdf
Scientific Editor Work List 52691-Scientific editor work list.pdf