Publication Name	World Journal of Gastroenterology
Manuscript ID	5297
Country	Italy

Received	2013-08-28 11:27
Peer-Review Started	2013-08-28 14:59
To Make the First Decision	2013-09-09 16:56
Return for Revision	2013-09-10 14:27
Revised	2013-09-30 00:05
Second Decision	2013-10-17 14:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-10-18 07:49
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-04 09:42
Publish the Manuscript Online	2013-12-18 09:53

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Bridging and downstaging treatments for hepatocellular carcinoma in patients on the waiting list for liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Maurizio Pompili, Giampiero Francica, Francesca Romana Ponziani, Roberto Iezzi and Alfonso Wolfango Avolio
Funding Agency and Grant Number
Corresponding Author	Maurizio Pompili, MD, Department of Internal Medicine, Università Cattolica del Sacro Cuore, Largo A. Gemelli, 8-00168 Roma, Italy. mpompili@rm.unicatt.it
Key Words	Hepatocellular carcinoma; Bridging treatment; Downstaging; Liver cirrhosis; Liver transplantation; Liver resection; Waiting list; Waiting time; Dropout rate
Core Tip	The bridging treatments for patients with hepatocellular carcinoma within Milan criteria listed for liver transplantation are useful in decreasing dropout rate from the waiting list and the experiences reported to date suggest a positive impact on post-transplant tumor recurrence and patient survival. The response to treatments may represent a surrogate marker of tumor biological aggressiveness and could be evaluated to prioritize hepatocellular carcinoma candidates in the waiting list. Advanced hepatocellular carcinoma may be downstaged to achieve the current conventional criteria for inclusion in the waiting list and successfully downstaged patients can achieve an excellent 5-year survival rate.
Publish Date	2013-12-18 09:53
Citation	Pompili M, Francica G, Ponziani FR, Iezzi R, Avolio AW. Bridging and downstaging treatments for hepatocellular carcinoma in patients on the waiting list for liver transplantation. World J Gastroenterol 2013; 19(43): 7515-7530
URL	http://www.wjgnet.com/1007-9327/full/v19/i43/7515.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i43.7515

Full Article (PDF)	WJG-19-7515.pdf
Manuscript File	5297-Review .docx
Answering Reviewers	5297-Answering Reviewers.pdf
Copyright License Agreement	5297-Copyright Assignment.pdf
Non-Native Speakers of English Editing Certificate	5297-Language Certificate.pdf
Peer-review Report	5297-Peer Review(s).pdf
Scientific Editor Work List	5297-Scientific editor work list.doc