| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Neurosciences |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Mariana Penteado Nucci, Igor Salerno Filgueiras, João Matias Ferreira, Fernando Anselmo de Oliveira, Leopoldo Penteado Nucci, Javier Bustamante Mamani, Gabriel Nery Albuquerque Rego and Lionel Fernel Gamarra |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR) |
CNPq-400856/2016-6 |
| São Paulo State Research Support Foundation |
FAPESP:2014/50983-3 |
| São Paulo State Research Support Foundation |
FAPESP:2016/21470-3 |
|
| Corresponding Author |
Lionel Fernel Gamarra, MSc, PhD, Academic Research, Associate Research Scientist, Postdoc, Professor, Reader in Health Technology Assessment, Senior Researcher, Statistician, Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, Avenida Albert Einstein, 627/701 – Morumbi, São Paulo 05529-060, Brazil. lgamarra@einstein.br |
| Key Words |
Stem cell; Nanoparticles; Homing; Tracking; Near-infrared fluorescence image; Cellular therapy |
| Core Tip |
The systematic review provided an up-to-date evaluation of stem cell (SC) migration homing, using nanoparticles based on the technical and scientific aspects and combined molecular images. Thus, the efficacy of SC therapy depends on the SC homing ability and engraftment into the injury site over a long period of time, providing functional and structural outcomes in preclinical studies, but limited evidence of outcomes in clinical studies. |
| Publish Date |
2020-05-26 14:31 |
| Citation |
Nucci MP, Filgueiras IS, Ferreira JM, Oliveira FA, Nucci LP, Mamani JB, Rego GNA, Gamarra LF. Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review. World J Stem Cells 2020; 12(5): 381-405 |
| URL |
https://www.wjgnet.com/1948-0210/full/v12/i5/381.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v12.i5.381 |
