Publication Name	World Journal of Gastroenterology
Manuscript ID	53381
Country	Romania

Received	2019-12-20 07:54
Peer-Review Started	2019-12-20 08:00
To Make the First Decision
Return for Revision	2020-01-12 06:46
Revised	2020-03-04 23:19
Second Decision	2020-03-08 15:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-03-09 06:19
Articles in Press	2020-03-09 06:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-03-20 02:35
Publish the Manuscript Online	2020-03-21 02:52

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Review
Article Title	Circulating microRNAs as non-invasive biomarkers for hepatitis B virus liver fibrosis
Manuscript Source	Invited Manuscript
All Author List	Diana Gabriela Iacob, Adelina Rosca and Simona Maria Ruta
ORCID	Author(s) ORCID Number Diana Gabriela Iacob http://orcid.org/0000-0003-2256-458X Adelina Rosca http://orcid.org/0000-0002-8003-2816 Simona Maria Ruta http://orcid.org/0000-0002-2492-6073
Funding Agency and Grant Number	Funding Agency Grant Number Ministerul Cercetarii si Inovarii, Programul 1, subprogramul 1.2. Performanta institutionala PFE_23/2018
Corresponding Author	Simona Maria Ruta, MD, PhD, Professor, Senior Researcher, Virology Department, Carol Davila University of Medicine and Pharmacy, Eroii Sanitari 8, Bucharest 050474, Romania. simona.ruta@umfcd.ro
Key Words	Hepatitis B virus; MicroRNA; Noncoding RNA; Liver fibrosis; Viral hepatitis; Non-invasive biomarkers
Core Tip	The current review analyses the available data on the role of microRNAs (miRNAs) in the development and progression of liver fibrosis by focusing on their potential use as diagnostic and prognostic biomarkers for hepatitis B virus-infected patients. Cellular and circulating miRNAs (in plasma or extracellular vesicles) offer a unique glimpse into the virus-host relationship and the pathogenesis of chronic hepatitis B virus infection. The differential regulation of intracellular and circulating miRNAs during the natural and on treatment evolution of chronic hepatitis B is discussed.
Publish Date	2020-03-21 02:52
Citation	Iacob D, Rosca A, Ruta SM. Circulating microRNAs as non-invasive biomarkers for hepatitis B virus liver fibrosis. World J Gastrenterol 2020; 26(11): 1113-1127
URL	https://www.wjgnet.com/1007-9327/full/v26/i11/1113.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i11.1113

Full Article (PDF)	WJG-26-1113.pdf
Full Article (Word)	WJG-26-1113.docx
Manuscript File	53381-Review.docx
Answering Reviewers	53381-Answering reviewers.pdf
Audio Core Tip	53381-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	53381-Conflict-of-interest statement.pdf
Copyright License Agreement	53381-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	53381-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	53381-Language certificate.pdf
Peer-review Report	53381-Peer-review(s).pdf
Scientific Misconduct Check	53381-Scientific misconduct check.pdf
Scientific Editor Work List	53381-Scientific editor work list.pdf