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Publication Name World Journal of Gastroenterology
Manuscript ID 53501
Country/Territory Egypt
2020-01-04 23:29
Peer-Review Started
2020-01-04 23:29
To Make the First Decision
Return for Revision
2020-02-24 22:44
2020-03-27 16:43
Second Decision
2020-05-27 06:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-28 03:04
Articles in Press
2020-05-28 03:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-06-03 02:15
Publish the Manuscript Online
2020-06-06 14:43
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title M2BPGi for assessing liver fibrosis in patients with hepatitis C treated with direct-acting antivirals
Manuscript Source Invited Conference Manuscripts
All Author List Shereen A Saleh, Mohamed M Salama, Marwan M Alhusseini and Ghada A Mohamed
Author(s) ORCID Number
Shereen A Saleh http://orcid.org/0000-0002-0984-1725
Mohamed M Salama http://orcid.org/0000-0001-9120-8971
Marwan M Alhusseini http://orcid.org/0000-0002-0480-5952
Ghada A Mohamed http://orcid.org/0000-0003-0320-1011
Funding Agency and Grant Number
Corresponding author Ghada A Mohamed, MD, Lecturer, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Khalifa El-Maamon St., Abbassia, Cairo 11341, Egypt. ghadaabdelrahman@med.asu.edu.eg
Key Words Hepatitis C virus; Liver fibrosis; Human Mac-2 binding protein; Antiviral agents; Sustained virologic response; Elastography
Core Tip For 12 wk, 80 chronic hepatitis C patients received a sofosbuvir/daclatasvir/± ribavirin treatment. All patients achieved sustained virologic response (SVR12). Serum Mac-2 binding protein glycosylation isomer (M2BPGi) levels, liver stiffness measurements, fibrosis-4 (FIB-4) and PAPAS index decreased significantly at SVR12. At baseline, M2BPGi was the best marker to distinguish patients with grade F4 fibrosis, patients with grade F2 from grade F0-1 fibrosis, patients with grade F3-4 from grade F0-2 fibrosis, and patients with grade F2-4 from grade F0-1 fibrosis. At SVR12, M2BPGi had the greatest AUCs for differentiating patients with grade F4 fibrosis, patients with grade F3 from grade F0-2 fibrosis, patients with grade F3-4 from grade F0-2 fibrosis, and patients with grade F2-4 from grade F0-1 fibrosis.
Publish Date 2020-06-06 14:43
Citation Saleh SA, Salama MM, Alhusseini MM, Mohamed GA. M2BPGi for assessing liver fibrosis in patients with hepatitis C treated with direct-acting antivirals. World J Gastroenterol 2020; 26(21): 2864-2876
Url https://www.wjgnet.com/1007-9327/full/v26/i21/2864.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i21.2864
Full Article (PDF) WJG-26-2864.pdf
Full Article (Word) WJG-26-2864.docx
Manuscript File 53501-Review.docx
Answering Reviewers 53501-Answering reviewers.pdf
Audio Core Tip 53501-Audio core tip.mp3
Biostatistics Review Certificate 53501-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 53501-Conflict-of-interest statement.pdf
Copyright License Agreement 53501-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 53501-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 53501-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 53501-Language certificate.pdf
Supplementary Material 53501-Supplementary material.pdf
Peer-review Report 53501-Peer-review(s).pdf
Scientific Misconduct Check 53501-Bing-Dou Y-2.png
Scientific Misconduct Check 53501-Scientific misconduct check.pdf
Scientific Editor Work List 53501-Scientific editor work list.pdf