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Articles Published Processes
4/21/2020 6:56:33 AM | Browse: 417 | Download: 578
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Received |
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2019-12-26 08:31 |
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Peer-Review Started |
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2019-12-26 08:31 |
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To Make the First Decision |
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Return for Revision |
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2020-02-18 20:53 |
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Revised |
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2020-03-23 19:35 |
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Second Decision |
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2020-03-26 09:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-03-26 21:05 |
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Articles in Press |
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2020-03-26 21:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-20 02:04 |
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Publish the Manuscript Online |
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2020-04-21 06:56 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Torque teno virus in liver diseases: On the way towards unity of view
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Vasiliy I Reshetnyak, Igor V Maev, Alexandr I Burmistrov, Igor A Chekmazov and Tatiana I Karlovich |
| ORCID |
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| Corresponding Author |
Vasiliy I Reshetnyak, DSc, MD, PhD, Full Professor, Department of Propaedeutic of Internal Diseases and Gastroenterology, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, p. 1, 20 Delegatskaya Street, Moscow 127473, Russia. vasiliy.reshetnyak@yandex.ru |
| Key Words |
Torque teno virus; Prevalence of torque teno virus; Torque teno virus in liver disease; Virome and torque teno virus; Torque teno virus and human immune status; |
| Core Tip |
The review is dedicated to torque teno virus (TTV) discovered in the late 20th century. It presents data on the morphofunctional properties of the virus, its immunobiology, prevalence, transmission routes, possible replication sites, methods for diagnosis and co-infection in liver diseases. The authors tried to analyze the information accumulated in the literature on these issues and to show the evolution of views on the importance of the virus to humans: from its hepatotropism to virome and a marker for the human immune status. Along with this, the review gives data suggesting that there are biochemical and histological changes in the liver and bile duct epithelium during TTV monoinfection. On the one hand, this information points to the possible replication of the virus in the cells of the liver and the epithelium of the bile ducts. On the other hand, the high prevalence of TTV in the population indicates its persistence in the body as a virome and a non-pathogenic virus. Moreover, the fortunately rare identification of the damaging effect of the virus on the cells of the liver and the epithelium of the bile ducts may be indirect evidence of its conditionally pathogenic properties. |
| Publish Date |
2020-04-21 06:56 |
| Citation |
Reshetnyak VI, Maev IV, Burmistrov AI, Chekmazov IA, Karlovich TI. Torque teno virus in liver diseases: On the way towards unity of view. World J Gastroenterol 2020; 26(15): 1691-1707 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i15/1691.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i15.1691 |
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