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4/23/2020 10:34:55 AM | Browse: 530 | Download: 1338
Publication Name World Journal of Hepatology
Manuscript ID 53641
Country/Territory Brazil
Received
2019-12-29 22:57
Peer-Review Started
2019-12-29 22:58
To Make the First Decision
2020-02-17 02:15
Return for Revision
2020-02-23 06:18
Revised
2020-02-28 14:25
Second Decision
2020-03-19 07:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-22 21:03
Articles in Press
2020-03-22 21:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-04-08 13:03
Publish the Manuscript Online
2020-04-23 10:34
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus
Manuscript Source Invited Manuscript
All Author List Cliviany Borges da Silva, Diego Alves Vieira, Luisa Freitas de Melo, Anna Luiza Soares Chagas, Adriana Dias Gomes, César Lúcio Lopes de Faria Jr, Rosângela Teixeira, Dulciene Maria de Magalhães Queiroz, Gifone Aguiar Rocha, Maria Marta Sarquis Soares, Juliana Maria Trindade Bezerra and Luciana Diniz Silva
ORCID
Author(s) ORCID Number
Cliviany Borges da Silva http://orcid.org/0000-0003-1060-9015
Diego Alves Vieira http://orcid.org/0000-0001-6847-8068
Luisa Freitas de Melo http://orcid.org/0000-0003-1225-8263
Anna Luiza Soares Chagas http://orcid.org/0000-0002-5966-5555
Adriana Dias Gomes http://orcid.org/0000-0001-7304-1864
César Lúcio Lopes de Faria Jr http://orcid.org/0000-0001-6753-4486
Rosângela Teixeira http://orcid.org/0000-0003-2192-722X
Dulciene Maria de Magalhães Queiroz http://orcid.org/0000-0003-1334-9423
Gifone Aguiar Rocha http://orcid.org/0000-0002-1858-3166
Maria Marta Sarquis Soares http://orcid.org/0000-0002-0847-7060
Juliana Maria Trindade Bezerra http://orcid.org/0000-0001-9840-6217
Luciana Diniz Silva http://orcid.org/0000-0003-0061-7361
Funding Agency and Grant Number
Funding Agency Grant Number
Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-02320-18
Corresponding Author Luciana Diniz Silva, MD, PhD, Academic Research, Associate Professor, Attending Doctor, Research Scientist, Department of Internal Medicine, Faculdade de Medicina, Universidade Federal de Minas Gerais, Av Alfredo Balena 190 s/255, Belo Horizonte 30720030, Minas Gerais, Brazil. lucianadinizsilva@gmail.com
Key Words Chronic Hepatitis C; Type 2 diabetes mellitus; Interleukin 6-174G/C gene promoter single nucleotide polymorphism; Blood hypertension; Healthy control subjects;
Core Tip Chronic hepatitis C is associated with type 2 diabetes mellitus. Previous studies have demonstrated associations between increased serum concentrations of Interleukin 6 (IL-6) and type 2 diabetes and advanced forms of liver disease. However, the role played by IL-6-174G/C single nucleotide polymorphism on the pathogenesis of hepatitis C virus-associated type 2 diabetes remains to be elucidated. To the best of our knowledge, this is the first study to demonstrate that the GC and GG genotypes of IL-6 are inversely associated with type 2 diabetes. We believe that our results may contribute to the understanding of the extra-hepatic manifestations in hepatitis C.
Publish Date 2020-04-23 10:34
Citation de Silva CB, Vieira DA, de Melo LF, Chagas ALS, Gomes AD, Faria Jr CLL, Teixeira R, Queiroz DM, Rocha GA, Soares MMS, de Bezerra JMT, Silva LD. Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus. World J Hepatol 2020; 12(4): 137-148
URL https://www.wjgnet.com/1948-5182/full/v12/i4/137.htm
DOI https://dx.doi.org/10.4254/wjh.v12.i4.137
Full Article (PDF) WJH-12-137.pdf
Full Article (Word) WJH-12-137.docx
STROBE Statement 53641-STROBE-Statement-revision.pdf
Manuscript File 53641-Review.docx
Answering Reviewers 53641-Answering reviewers.pdf
Audio Core Tip 53641-Audio core tip.mp3
Biostatistics Review Certificate 53641-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 53641-Conflict-of-interest statement.pdf
Copyright License Agreement 53641-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53641-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 53641-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 53641-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 53641-Language certificate.pdf
Peer-review Report 53641-Peer-review(s).pdf
Scientific Misconduct Check 53641-Scientific misconduct check.pdf
Scientific Editor Work List 53641-Scientific editor work list.pdf