| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Gamma-glutamyl transferase and cardiovascular risk in nonalcoholic fatty liver disease: The Gut and Obesity Asia initiative
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Panyavee Pitisuttithum, Wah-Kheong Chan, George Boon-Bee Goh, Jian-Gao Fan, Myeong Jun Song, Phunchai Charatcharoenwitthaya, Ajay Duseja, Yock-Young Dan, Kento Imajo, Atsushi Nakajima, Khek-Yu Ho, Khean-Lee Goh, Vincent Wai-Sun Wong and Sombat Treeprasertsuk |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sombat Treeprasertsuk, MD, PhD, Professor, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Rama4 Road Pathumwan District, Bangkok 10330, Thailand. battan5410@gmail.com |
| Key Words |
Nonalcoholic fatty liver disease; Gamma glutamyl transferase; QRISK; Cardiovascular risk; Gut and obesity in Asia; |
| Core Tip |
The median 10-year cardiovascular disease risk of nonalcoholic fatty liver disease (NAFLD) patients according to QRISK2 score was higher than that of healthy individuals of the same age, sex, and ethnicity. Apart from traditional risk factors, advanced fibrosis is a predictor for high risk cardiovascular disease in NAFLD patients. However, the baseline gamma-glutamyl transferase level and high gamma-glutamyl transferase quartile cannot be used to predict cardiovascular risk in patients with established NAFLD. |
| Publish Date |
2020-05-21 12:02 |
| Citation |
Pitisuttithum P, Chan WK, Goh GBB, Fan JG, Song MJ, Charatcharoenwitthaya P, Duseja A, Dan YY, Imajo K, Nakajima A, Ho KY, Goh KL, Wong VWS, Treeprasertsuk S. Gamma-glutamyl transferase and cardiovascular risk in nonalcoholic fatty liver disease: The Gut and Obesity Asia initiative. World J Gastroenterol 2020; 26(19): 2416-2426 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i19/2416.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i19.2416 |
