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5/21/2020 12:02:13 PM | Browse: 17 | Download: 12
Publication Name World Journal of Gastroenterology
Manuscript ID 53914
Country/Territory China
Received
2020-01-01 04:47
Peer-Review Started
2020-01-01 04:50
To Make the First Decision
Return for Revision
2020-01-16 20:18
Revised
2020-03-27 07:47
Second Decision
2020-04-27 10:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-04-27 23:31
Articles in Press
2020-04-27 23:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-05-02 13:36
Typeset the Manuscript
2020-05-19 10:21
Publish the Manuscript Online
2020-05-21 12:02
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Pancreatic neuroendocrine tumors: A review of serum biomarkers, staging, and management
Manuscript Source Invited Manuscript
All Author List Zu-Yi Ma, Yuan-Feng Gong, Hong-Kai Zhuang, Zi-Xuan Zhou, Shan-Zhou Huang, Yi-Ping Zou, Bo-Wen Huang, Zhong-Hai Sun, Chuan-Zhao Zhang, Yun-Qiang Tang and Bao-Hua Hou
ORCID
Author(s) ORCID Number
Zu-Yi Ma http://orcid.org/0000-0002-8517-7600
Yuan-Feng Gong http://orcid.org/0000-0001-7742-6286
Hong-Kai Zhuang http://orcid.org/0000-0002-4106-8736
Zi-Xuan Zhou http://orcid.org/0000-0002-2070-2304
Shan-Zhou Huang http://orcid.org/0000-0002-7575-5841
Yi-Ping Zou http://orcid.org/0000-0003-2880-2147
Bo-Wen Huang http://orcid.org/0000-0003-4588-659X
Zhong-Hai Sun http://orcid.org/0000-0003-3254-4371
Chuan-Zhao Zhang http://orcid.org/0000-0001-5567-0325
Yun-Qiang Tang http://orcid.org/0000-0003-3185-8731
Bao-Hua Hou http://orcid.org/0000-0001-8734-9085
Funding Agency and Grant Number
Funding Agency Grant Number
Guangzhou Health and Family Planning Technology Project 20191A011096
National Natural Science Foundation of China 81602172
Guangdong Provincial Science and Technology Plan Projects 2016A030313769
Guangzhou Science and Technology Plan of Scientifc Research Projects 201707010323
Corresponding author Bao-Hua Hou, MD, PhD, Director, Professor, Surgeon, Department of General Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, No.106 Zhongshan 2nd Rd, Yuexiu District, Guangzhou 510080, Guangdong Province, China. houbaohuahbp@163.com
Keywords Pancreatic neuroendocrine tumor; Serum biomarkers; Staging; Grading; Management; Therapy
Core Tip Pancreatic neuroendocrine tumors are a heterogeneous group of tumors with complicated treatment. There are several highlights of our manuscript. Firstly, we summarized conventional and new advances in serum biomarkers, like circulating tumor cells, multiple transcripts analysis, miRNAs profile and cytokines. Then we reviewed the changes of each guidelines of grading and staging systems and the clinical evidence behind them. Lastly surgical resection is still the only curative therapeutic option for localized pancreatic neuroendocrine tumors. Great progresses have been achieved in drug therapy and the combination with local control treatments. We summarize new advances in detail and provided potential strategies for neuroendocrine tumor associated with liver metastases management.
Publish Date 2020-05-21 12:02
Citation Ma ZY, Gong YF, Zhuang HK, Zhou ZX, Huang SZ, Zou YP, Huang BW, Sun ZH, Zhang CZ, Tang YQ, Hou BH. Pancreatic neuroendocrine tumors: A review of serum biomarkers, staging, and management. World J Gastroenterol 2020; 26(19): 2305-2322
Url https://www.wjgnet.com/1007-9327/full/v26/i19/2305.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i19.2305
Full Article (PDF) WJG-26-2305.pdf
Full Article (Word) WJG-26-2305.docx
Manuscript File 53914-Review_WangTQ.docx
Answering Reviewers 53914-Answering reviewers.pdf
Audio Core Tip 53914-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 53914-Conflict-of-interest statement.pdf
Copyright License Agreement 53914-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53914-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 53914-Language certificate.pdf
Peer-review Report 53914-Peer-review(s).pdf
Scientific Misconduct Check 53914-Scientific misconduct check.pdf
Scientific Editor Work List 53914-Scientific editor work list.pdf