| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Selective lateral lymph node dissection after neoadjuvant chemoradiotherapy in rectal cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Nan Chen, Zheng Liu, Zhi-Jie Wang, Shi-Wen Mei, Hai-Yu Shen, Juan Li, Wei Pei, Zheng Wang, Xi-Shan Wang, Jun Yu and Qian Liu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Medicine and Health Technology Innovation Project of Chinese Academy of Medical Sciences |
2017-12M-1-006 |
| China Scholarship Council |
CSC201906210471 |
|
| Corresponding Author |
Qian Liu, MD, Chief Doctor, Professor, Surgeon, Teacher, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com |
| Key Words |
Rectal neoplasms; Neoadjuvant therapies; Lateral lymph node dissection; Locoregional recurrence; Lymphatic metastasis; Total mesorectal excision |
| Core Tip |
Lateral lymph node metastasis is one of the leading causes of local recurrence in advanced mid or low rectal cancer patients. Lateral local recurrence remains a significant clinical problem associated with severe morbidity, low salvage likelihood. There is an East (mainly Japan)-West divide regarding the management of lateral lymph nodes associated with lower rectal cancer. Preoperative chemoradiotherapy followed by total mesorectal excision is standard procedure in the west. Our study shows that lateral lymph node metastasis cannot eradicate by neoadjuvant chemoradiotherapy. Selective total mesorectal excision plus lateral lymph node dissection should be performed in advanced mid or low rectal cancer patients. |
| Publish Date |
2020-06-06 14:43 |
| Citation |
Chen JN, Liu Z, Wang ZJ, Mei SW, Shen HY, Li J, Pei W, Wang Z, Wang XS, Yu J, Liu Q. Selective lateral lymph node dissection after neoadjuvant chemoradiotherapy in rectal cancer. World J Gastroenterol 2020; 26(21): 2877-2888 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i21/2877.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i21.2877 |
