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5/13/2020 1:27:23 AM | Browse: 532 | Download: 771
Publication Name World Journal of Clinical Infectious Diseases
Manuscript ID 54579
Country United States
Received
2020-02-07 16:14
Peer-Review Started
2020-02-07 16:15
To Make the First Decision
Return for Revision
2020-03-05 21:52
Revised
2020-03-25 13:24
Second Decision
2020-04-29 12:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-05 15:15
Articles in Press
2020-05-05 15:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-05-09 03:42
Publish the Manuscript Online
2020-05-13 01:27
ISSN 2220-3176 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Basic Study
Article Title GadE regulates fliC gene transcription and motility in Escherichia coli
Manuscript Source Invited Manuscript
All Author List William R Schwan, Nicole L Flohr, Abigail R Multerer and Jordan C Starkey
ORCID
Author(s) ORCID Number
William R Schwan http://orcid.org/0000-0003-3076-1815
Nicole L Flohr http://orcid.org/0000-0003-0445-124X
Abigail R Multerer http://orcid.org/0000-0001-6789-6268
Jordan C Starkey http://orcid.org/0000-0001-9160-8588
Funding Agency and Grant Number
Funding Agency Grant Number
National Institutes of Health 1R15AI-065432-01a2
Corresponding Author William R Schwan, PhD, Professor, Department of Microbiology, University of Wisconsin-La Crosse, 1725 State St, La Crosse, WI 54601, United States. wschwan@uwlax.edu
Key Words Escherichia coli; Flagella; GadE; Motility; Acid response; fliC
Core Tip Escherichia coli (E. coli) is the number one cause of urinary tract infections in women. The infections are the result of the E. coli cells ascending the urinary tract via flagella presented on the outside of the cells. In this study, we have shown that E. coli grown in a low pH/high-osmolarity environment display transcriptional repression of the fliC flagellin subunit gene. Furthermore, we demonstrate that GadE may regulate fliC transcription and subsequent motility of the E. coli cells.
Publish Date 2020-05-13 01:27
Citation Schwan WR, Flohr NL, Multerer AR, Starkey JC. GadE regulates fliC gene transcription and motility in Escherichia coli. World J Clin Infect Dis 2020; 10(1): 14-23
URL https://www.wjgnet.com/2220-3176/full/v10/i1/14.htm
DOI https://dx.doi.org/10.5495/wjcid.v10.i1.14
Full Article (PDF) WJCID-10-14.pdf
Full Article (Word) WJCID-10-14.docx
Manuscript File 54579-Review.docx
Answering Reviewers 54579-Answering reviewers.pdf
Audio Core Tip 54579-Audio core tip.wav
Biostatistics Review Certificate 54579-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 54579-Conflict-of-interest statement.pdf
Copyright License Agreement 54579-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54579-Grant application form(s).pdf
Peer-review Report 54579-Peer-review(s).pdf
Scientific Misconduct Check 54579-CrossCheck.png
Scientific Misconduct Check 54579-Scientific misconduct check.pdf
Scientific Editor Work List 54579-Scientific editor work list.pdf