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Publication Name World Journal of Gastroenterology
Manuscript ID 54868
Country/Territory United States
2020-02-25 19:29
Peer-Review Started
2020-02-25 19:30
To Make the First Decision
Return for Revision
2020-04-22 23:06
2020-05-02 01:58
Second Decision
2020-05-13 07:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-13 23:11
Articles in Press
2020-05-13 23:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-05-27 09:14
Publish the Manuscript Online
2020-05-28 13:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Treatment of gastrointestinal bleeding in left ventricular assist devices: A comprehensive review
Manuscript Source Invited Manuscript
All Author List Srikanth Vedachalam, Gokulakrishnan Balasubramanian, Garrie J Haas and Somashekar G Krishna
Author(s) ORCID Number
Srikanth Vedachalam http://orcid.org/0000-0003-1499-335X
Gokulakrishnan Balasubramanian http://orcid.org/0000-0003-1099-8356
Garrie J Haas http://orcid.org/0000-0002-4189-6136
Somashekar G Krishna http://orcid.org/0000-0001-5748-7890
Funding Agency and Grant Number
Corresponding Author Somashekar G Krishna, MD, Associate Professor, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University College of Medicine, 395 W. 12th Avenue, Suite 262, Columbus, OH 43210, United States. somashekar.krishna@osumc.edu
Key Words Left ventricular assist device; Push enteroscopy; Double balloon enteroscopy; Video capsule endoscopy; Octreotide; Bevacizumab; Gastrointestinal bleeding
Core Tip Left ventricular assist devices are becoming increasingly common as life-prolonging therapy in advanced heart failure. However, left ventricular assist devices have shown high rates of gastrointestinal bleeding with 18%-40% of patients having episodes of bleed. Arteriovenous malformations are primarily responsible, which can be both challenging to control and cause many patients to discontinue essential anti-platelet and anti-coagulation therapies. Small bowel lesions are common in this population, frequently requiring small bowel endoscopic evaluation. For refractory cases, medical management is required including octreotide, thalidomide, angiotensin converting enzyme inhibitors/angiotensin II receptor blockers, estrogen-based therapies, desmopressin, doxycycline or bevacizumab to prevent further gastrointestinal bleeding.
Publish Date 2020-05-28 13:08
Citation Vedachalam S, Balasubramanian G, Haas GJ, Krishna SG. Treatment of gastrointestinal bleeding in left ventricular assist devices: A comprehensive review. World J Gastroenterol 2020; 26(20): 2550-2558
Url https://www.wjgnet.com/1007-9327/full/v26/i20/2550.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i20.2550
Full Article (PDF) WJG-26-2550.pdf
Full Article (Word) WJG-26-2550.docx
Manuscript File 54868-Review.docx
Answering Reviewers 54868-Answering reviewers.pdf
Audio Core Tip 54868-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 54868-Conflict-of-interest statement.pdf
Copyright License Agreement 54868-Copyright license agreement.pdf
Peer-review Report 54868-Peer-review(s).pdf
Scientific Misconduct Check 54868-Bing-Yan JP-1.png
Scientific Misconduct Check 54868-Scientific misconduct check.pdf
Scientific Editor Work List 54868-Scientific editor work list.pdf