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5/26/2020 2:31:16 PM | Browse: 713 | Download: 1098
Publication Name World Journal of Stem Cells
Manuscript ID 55007
Country/Territory Switzerland
Received
2020-02-27 17:23
Peer-Review Started
2020-02-27 17:23
To Make the First Decision
Return for Revision
2020-04-07 23:24
Revised
2020-04-19 15:20
Second Decision
2020-04-29 12:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-05 15:13
Articles in Press
2020-05-05 15:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-05-14 03:51
Publish the Manuscript Online
2020-05-26 14:31
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title Molecular modulation of autophagy: New venture to target resistant cancer stem cells
Manuscript Source Invited Manuscript
All Author List Harpreet K Mandhair, Miroslav Arambasic, Urban Novak and Ramin Radpour
ORCID
Author(s) ORCID Number
Harpreet K Mandhair http://orcid.org/0000-0001-8753-7078
Miroslav Arambasic http://orcid.org/0000-0003-0296-1174
Urban Novak http://orcid.org/0000-0001-7642-2101
Ramin Radpour http://orcid.org/0000-0002-5632-7833
Funding Agency and Grant Number
Corresponding Author Ramin Radpour, MSc, PhD, Lecturer, Senior Researcher, Tumor Immunology, Department for BioMedical Research (DBMR), University of Bern, Murtenstrasse 35, Bern 3008, Switzerland. ramin.radpour@dbmr.unibe.ch
Key Words Autophagy; Cancer stem cells; Cancer cells; Cancer therapy; Therapeutic resistance; Cancer metastasis
Core Tip Cancer stem cells (CSCs) are a distinct subpopulation in the tumor bulk that are highly plastic, and autophagy has been suggested to modulate their stemness and development during cancer progression. Autophagy is a pro-survival mechanism used by cancer cells to provide bioenergetic substrates. Therefore, dissecting the role of autophagy in cancer propagation can theoretically lead to a more efficient cancer treatment via the modulation of autophagy, in combination with chemotherapeutics to sensitize and target CSCs. This review summarizes the divergent role of autophagy in CSCs and cancer cells and attempts to elucidate the molecular mechanisms involved.
Publish Date 2020-05-26 14:31
Citation Mandhair HK, Arambasic M, Novak U, Radpour R. Molecular modulation of autophagy: New venture to target resistant cancer stem cells. World J Stem Cells 2020; 12(5): 303-322
URL https://www.wjgnet.com/1948-0210/full/v12/i5/303.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i5.303
Full Article (PDF) WJSC-12-303.pdf
Full Article (Word) WJSC-12-303.docx
Manuscript File 55007-Review.docx
Answering Reviewers 55007-Answering reviewers.pdf
Audio Core Tip 55007-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 55007-Conflict-of-interest statement.pdf
Copyright License Agreement 55007-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 55007-Language certificate.pdf
Peer-review Report 55007-Peer-review(s).pdf
Scientific Misconduct Check 55007-CrossCheck.png
Scientific Misconduct Check 55007-Bing-Dou Y-2.png
Scientific Misconduct Check 55007-Scientific misconduct check.pdf
Scientific Editor Work List 55007-Scientific editor work list.pdf