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7/26/2020 8:24:58 AM | Browse: 550 | Download: 1095
Publication Name World Journal of Stem Cells
Manuscript ID 55077
Country/Territory France
Received
2020-02-28 22:20
Peer-Review Started
2020-02-28 22:22
To Make the First Decision
Return for Revision
2020-04-18 21:19
Revised
2020-05-19 16:07
Second Decision
2020-06-08 09:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-06-10 20:06
Articles in Press
2020-06-10 20:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-07-24 08:43
Publish the Manuscript Online
2020-07-26 08:24
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title Involvement of glycated albumin in adipose-derived-stem cell-mediated interleukin 17 secreting T helper cell activation
Manuscript Source Invited Manuscript
All Author List Julien Pestel, Maud Robert, Sara Corbin, Hubert Vidal and Assia Eljaafari
ORCID
Author(s) ORCID Number
Julien Pestel http://orcid.org/0000-0002-2438-5705
Maud Robert http://orcid.org/0000-0002-0176-5326
Sara Corbin http://orcid.org/0000-0003-4790-0439
Hubert Vidal http://orcid.org/0000-0002-9467-0317
Assia Eljaafari http://orcid.org/0000-0002-8300-540X
Funding Agency and Grant Number
Corresponding Author Assia Eljaafari, MD, PhD, Doctor, Senior Scientist, CarMeN laboratory, INSERM U1060, University Claude Bernard Lyon 1 and Hospices Civils de Lyon, Batiment CENS-ELI, Centre Hospitalier Lyon Sud, 165 chemin du Grand Revoyet, Pierre Bénite 69310, France. assia.eljaafari@univ-lyon1.fr
Key Words Interleukin 17 secreting T cells; Lean adipose tissue; Type 1 diabetes; Advanced glycation end products; Adipose-derived stem cells;
Core Tip Using a coculture model with human lean adipose-derived stem cells (ASC) and mononuclear cells, we have shown in this study that glycated human serum albumin (G-HSA) enhances lean ASC-mediated interleukin (IL)-17A, interferon gamma and tumor necrosis factor alpha secretion. This effect involved the advanced glycated end products (AGE)/Receptor of advanced glycated end products (RAGE) axis as assessed by anti-RAGE blocking antibodies and was associated with increased expression of RAGE and human leukocyte antigen-DR molecules. Thus, our results demonstrated that G-HSA potentiated lean ASC-mediated IL-17A production in adipose tissues, suggesting a new mechanism by which AGE could contribute to type 1 diabetes pathophysiology.
Publish Date 2020-07-26 08:24
Citation Pestel J, Robert M, Corbin S, Vidal H, Eljaafari A. Involvement of Glycated Albumin in adipose-derived-stem cell-mediated Th17 cell activation. World J Stem Cells 2020; 12(7): 621-632
URL https://www.wjgnet.com/1948-0210/full/v12/i7/621.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i7.621
Full Article (PDF) WJSC-12-621.pdf
Full Article (Word) WJSC-12-621.docx
Manuscript File 55077-Review.docx
Answering Reviewers 55077-Answering reviewers.pdf
Audio Core Tip 55077-Audio core tip.m4a
Biostatistics Review Certificate 55077-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 55077-Conflict-of-interest statement.pdf
Copyright License Agreement 55077-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 55077-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 55077-Language certificate.pdf
Supplementary Material 55077-Supplementary material.pdf
Peer-review Report 55077-Peer-review(s).pdf
Scientific Misconduct Check 55077-Bing-Tang JZ-1.png
Scientific Misconduct Check 55077-Bing-Liu M-2.PNG
Scientific Misconduct Check 55077-Scientific misconduct check.pdf
Scientific Editor Work List 55077-Scientific editor work list.pdf