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9/22/2020 6:23:06 AM | Browse: 30 | Download: 51
Publication Name World Journal of Stem Cells
Manuscript ID 55126
Country/Territory South Korea
Received
2020-03-20 09:14
Peer-Review Started
2020-03-20 09:23
To Make the First Decision
Return for Revision
2020-04-29 21:55
Revised
2020-06-20 02:59
Second Decision
2020-07-17 09:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-19 21:38
Articles in Press
2020-07-19 21:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-07-23 23:38
Typeset the Manuscript
2020-09-18 17:10
Publish the Manuscript Online
2020-09-22 06:23
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Basic Study
Article Title Human mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms
Manuscript Source Unsolicited Manuscript
All Author List Yunejin Song, Jung-Yeon Lim, Taekyu Lim, Keon-Il Im, Nayoun Kim, Young-Sun Nam, Young-Woo Jeon, Jong Chul Shin, Hyun Sun Ko, In Yang Park and Seok-Goo Cho
ORCID
Author(s) ORCID Number
Yunejin Song http://orcid.org/0000-0002-9379-422X
Jung-Yeon Lim http://orcid.org/0000-0001-5903-8810
Taekyu Lim http://orcid.org/0000-0002-3427-6705
Keon-Il Im http://orcid.org/0000-0003-2811-9815
Nayoun Kim http://orcid.org/0000-0001-8317-2921
Young-Sun Nam http://orcid.org/0000-0002-9327-5745
Young-Woo Jeon http://orcid.org/0000-0003-3362-8200
Jong Chul Shin http://orcid.org/0000-0003-0360-2309
Hyun Sun Ko http://orcid.org/0000-0001-6310-6206
In Yang Park http://orcid.org/0000-0002-9458-2886
Seok-Goo Cho http://orcid.org/0000-0002-5429-4839
Funding Agency and Grant Number
Funding Agency Grant Number
Korean Health Technology Rnd Project HI16C2178
Corresponding Author Seok-Goo Cho, MD, PhD, Professor, Division of Hematology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Banpodaero 222, Seocho-Gu, Seoul 06591, South Korea. chosg@catholic.ac.kr
Key Words Mesenchymal stem cells; Graft-versus-host disease; Umbilical cord; Cell therapy; Xenogeneic mouse model; Immunomodulation
Core Tip Mesenchymal stem cells (MSCs) have been considered as a therapeutic approach to treat graft-versus-host disease because of their unique immunomodulatory abilities. Here, we compared and analyzed the differences and similarities between umbilical cord-derived MSCs (UC-MSCs) and bone marrow-derived MSCs (BM-MSCs) due to the growing needs for new sources of MSCs. We suggest that UC-MSCs and BM-MSCs exhibit similar immunosuppression in different mechanisms, and UC-MSCs have potentials to substitute BM-MSCs as cell therapy products.
Publish Date 2020-09-22 06:23
Citation Song Y, Lim JY, Lim T, Im KI, Kim N, Nam YS, Jeon YW, Shin JC, Ko HS, Park IY, Cho SG. Human mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms. World J Stem Cells 2020; 12(9): 1032-1049
Url https://www.wjgnet.com/1948-0210/full/v12/i9/1032.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i9.1032
Full Article (PDF) WJSC-12-1032.pdf
Full Article (Word) WJSC-12-1032.docx
Manuscript File 55126-Review-Filipodia.docx
Answering Reviewers 55126-Answering reviewers.pdf
Audio Core Tip 55126-Audio core tip.mp3
Biostatistics Review Certificate 55126-Biostatistics statement.PDF
Conflict-of-Interest Disclosure Form 55126-Conflict-of-interest statement.pdf
Copyright License Agreement 55126-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55126-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 55126-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 55126-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 55126-Language certificate.pdf
Peer-review Report 55126-Peer-review(s).pdf
Scientific Misconduct Check 55126-Bing-Wang JL-1.jpg
Scientific Misconduct Check 55126-Scientific misconduct check.pdf
Scientific Editor Work List 55126-Scientific editor work list.pdf