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9/10/2020 5:57:28 AM | Browse: 626 | Download: 1061
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 56229
Country China
Received
2020-04-22 07:12
Peer-Review Started
2020-04-22 07:14
To Make the First Decision
Return for Revision
2020-04-26 17:39
Revised
2020-07-16 07:07
Second Decision
2020-08-14 09:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-16 18:13
Articles in Press
2020-08-16 18:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-08-28 08:35
Typeset the Manuscript
2020-09-07 02:04
Publish the Manuscript Online
2020-09-10 05:57
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Response of human epidermal growth factor receptor 2-positive colorectal cancer to lapatinib monotherapy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ji-Lin Guan, Jian-Hua Liu, Qing Wang, Yu-Wei Cong, Yao-Xu Chen, Ke-Fei Huang, Meng-Li Huang and Ling Huang
ORCID
Author(s) ORCID Number
Ji-Lin Guan http://orcid.org/0000-0001-5224-5892
Jian-Hua Liu http://orcid.org/0000-0003-3903-6038
Qing Wang http://orcid.org/0000-0002-8780-0638
Yu-Wei Cong http://orcid.org/0000-0001-7107-7820
Yao-Xu Chen http://orcid.org/0000-0002-8850-4267
Ke-Fei Huang http://orcid.org/0000-0002-1377-342X
Meng-Li Huang http://orcid.org/0000-0003-0169-7906
Ling Huang http://orcid.org/0000-0002-7684-1020
Funding Agency and Grant Number
Corresponding Author Ling Huang, MD, Director, Doctor, Professor, Department of Oncology, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, No. 123, Hui Fuxi Road, Yuexiu District, Guangzhou 510655, Guangdong Province, China. 13710351111@139.com
Key Words Human epidermal growth factor receptor 2; Colorectal cancer; Lapatinib; Circulating tumor deoxyribonucleic acid; Case report;
Core Tip While dual anti- human epidermal growth factor receptor 2 (HER2) therapies are recommend as standard treatment for HER2-positive advanced colorectal cancer, anti-HER2 monotherapy is rarely used to treat this population. This case is the first report of a HER2-positive RAS/BRAF-wild-type metastatic colorectal cancer patient achieving partial response following lapatinib monotherapy without serious adverse events. Next generation sequencing based circulating tumor deoxyribonucleic acid testing played an essential role in both treatment decision and efficacy/resistance monitoring.
Publish Date 2020-09-10 05:57
Citation Guan JL, Liu JH, Wang Q, Cong YW, Chen YX, Huang KF, Huang ML, Huang L. Response of human epidermal growth factor receptor 2-positive colorectal cancer to lapatinib monotherapy: A case report. World J Gastrointest Oncol 2020; 12(9): 1065-1072
URL https://www.wjgnet.com/1948-5204/full/v12/i9/1065.htm
DOI https://dx.doi.org/10.4251/wjgo.v12.i9.1065
Full Article (PDF) WJGO-12-1065.pdf
Full Article (Word) WJGO-12-1065.docx
CARE Checklist–2016 56229-CARE-Checklist–2016-revision_0632.pdf
Manuscript File 56229-Review_WangTQ.docx
Answering Reviewers 56229-Answering reviewers.pdf
Audio Core Tip 56229-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 56229-Conflict-of-interest statement.pdf
Copyright License Agreement 56229-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 56229-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 56229-Language certificate.pdf
Supplementary Material 56229-Supplementary material.pdf
Peer-review Report 56229-Peer-review(s).pdf
Scientific Misconduct Check 56229-Bing-Zhang H-1.png
Scientific Misconduct Check 56229-Scientific misconduct check.pdf
Scientific Editor Work List 56229-Scientific editor work list.pdf